ChemicalBook >> CAS DataBase List >>(-)-BICUCULLINE METHBROMIDE
(-)-BICUCULLINE METHBROMIDE
- CAS No.
- 66016-70-4
- Chemical Name:
- (-)-BICUCULLINE METHBROMIDE
- Synonyms
- d-Bicuculline methobromide;(-)-BICUCULLINE METHBROMIDE;1(S),9(R)-(-)-Bicuculline methbromide;1(s),9(r)-(-)-bicuculline methobromide;(+)-Bicuculline methobromide|||d-Bicuculline methobromide|||(+)-Bicuculline methobromide;(6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;[r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide;(5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1)
- CBNumber:
- CB3496965
- Molecular Formula:
- C21H20NO6.Br
- Molecular Weight:
- 462.294
- MDL Number:
- MFCD00055149
- MOL File:
- 66016-70-4.mol
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS06,GHS09 |
---|---|
Signal word | Danger |
Hazard statements | H300-H311+H331-H410 |
Precautionary statements | P273-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 |
Hazard Codes | T+,N |
Risk Statements | 24-28-50 |
Safety Statements | 24/25-61-45-36/37-28 |
RIDADR | UN 1544 6.1/PG 2 |
WGK Germany | 3 |
(-)-BICUCULLINE METHBROMIDE price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | B7561 | 1(S),9(R)-(?)-Bicuculline methbromide ≥98% (HPLC), solid | 66016-70-4 | 25mg | $173 | 2024-03-01 | Buy |
Sigma-Aldrich | B7561 | 1(S),9(R)-(?)-Bicuculline methbromide ≥98% (HPLC), solid | 66016-70-4 | 125mg | $724 | 2024-03-01 | Buy |
(-)-BICUCULLINE METHBROMIDE Chemical Properties,Uses,Production
Uses
1(S),9(R)-(-)-Bicuculline methbromide has been used:
- as a γ-aminobutyric acid (GABAA) receptor A antagonist: in cortical neuron culture
- in artificial cerebrospinal fluid (ACSF) formature dentate granule neurons
- in hypothalamic explant cultures
Biochem/physiol Actions
1(S),9(R)-(?)-Bicuculline methbromide is a GABAA receptor antagonist, which blocks Ca2+-activated potassium (SK) channels. It is the water-soluble derivative of (+)-bicuculline.
storage
Store at RT
(-)-BICUCULLINE METHBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(-)-BICUCULLINE METHBROMIDE Suppliers
Global( 7)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4578 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28091 | 58 |
Supplier | Advantage |
---|---|
Aladdin Scientific | 58 |
Sigma-Aldrich | 80 |
Nantong QuanYi Biotechnology Co., Ltd | 58 |
TargetMol Chemicals Inc. | 58 |
(5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1)
1(S),9(R)-(-)-Bicuculline methbromide
(-)-BICUCULLINE METHBROMIDE
[r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide
1(s),9(r)-(-)-bicuculline methobromide
(6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
d-Bicuculline methobromide
(+)-Bicuculline methobromide|||d-Bicuculline methobromide|||(+)-Bicuculline methobromide
66016-70-4