ChemicalBook >> CAS DataBase List >>N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI
- CAS No.
- 300670-16-0
- Chemical Name:
- N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI
- Synonyms
- N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI;C2-8 (polyQ aggregation inhibitor C2-8);Polyglutamine Aggregation Inhibitor III, C2-8;Benzamide, N-(4-bromophenyl)-3-(((4-bromophenyl)amino)sulfonyl);N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide >=98% (HPLC), solid
- CBNumber:
- CB3503193
- Molecular Formula:
- C19H14Br2N2O3S
- Molecular Weight:
- 510.2
- MDL Number:
- MFCD00355835
- MOL File:
- 300670-16-0.mol
Last updated:2023-06-08 09:02:49
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | B3436 | N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide ≥98% (HPLC), solid | 300670-16-0 | 5mg | $241 | 2024-03-01 | Buy |
Sigma-Aldrich | B3436 | N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide ≥98% (HPLC), solid | 300670-16-0 | 25mg | $738 | 2024-03-01 | Buy |
Cayman Chemical | 21177 | C2-8 ≥98% | 300670-16-0 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 21177 | C2-8 ≥98% | 300670-16-0 | 5mg | $141 | 2024-03-01 | Buy |
Cayman Chemical | 21177 | C2-8 ≥98% | 300670-16-0 | 10mg | $243 | 2024-03-01 | Buy |
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Chemical Properties,Uses,Production
Description
C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington''s disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2 transgenic mouse model of Huntington''s disease.
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Preparation Products And Raw materials
Raw materials
Preparation Products
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Suppliers
Global( 14)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9943 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 5585 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28091 | 58 |
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI
Benzamide, N-(4-bromophenyl)-3-(((4-bromophenyl)amino)sulfonyl)
Polyglutamine Aggregation Inhibitor III, C2-8
C2-8
(polyQ aggregation inhibitor C2-8)
N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide >=98% (HPLC), solid
300670-16-0