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ChemicalBook >> CAS DataBase List >>N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI

N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI

N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Structure
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI structure
CAS No.
300670-16-0
Chemical Name:
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI
Synonyms
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI;C2-8 (polyQ aggregation inhibitor C2-8);Polyglutamine Aggregation Inhibitor III, C2-8;Benzamide, N-(4-bromophenyl)-3-(((4-bromophenyl)amino)sulfonyl);N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide >=98% (HPLC), solid
CBNumber:
CB3503193
Molecular Formula:
C19H14Br2N2O3S
Molecular Weight:
510.2
MDL Number:
MFCD00355835
MOL File:
300670-16-0.mol
Last updated:2023-06-08 09:02:49
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N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Properties

Density 1.760±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ~20 mg/mL
pka 7.49±0.10(Predicted)
form solid
color off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H413
Precautionary statements  P273-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B3436 N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide ≥98% (HPLC), solid 300670-16-0 5mg $241 2024-03-01 Buy
Sigma-Aldrich B3436 N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide ≥98% (HPLC), solid 300670-16-0 25mg $738 2024-03-01 Buy
Cayman Chemical 21177 C2-8 ≥98% 300670-16-0 1mg $32 2024-03-01 Buy
Cayman Chemical 21177 C2-8 ≥98% 300670-16-0 5mg $141 2024-03-01 Buy
Cayman Chemical 21177 C2-8 ≥98% 300670-16-0 10mg $243 2024-03-01 Buy
Product number Packaging Price Buy
B3436 5mg $241 Buy
B3436 25mg $738 Buy
21177 1mg $32 Buy
21177 5mg $141 Buy
21177 10mg $243 Buy

N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Chemical Properties,Uses,Production

Description

C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington''s disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2 transgenic mouse model of Huntington''s disease.

N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Preparation Products And Raw materials

Raw materials

Preparation Products

N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32836 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9943 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5585 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Shanghai Chaolan Chemical Technology Center 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
N-(4-BROMOPHENYL)-3-{[(4-BROMOPHENYL)AMI Benzamide, N-(4-bromophenyl)-3-(((4-bromophenyl)amino)sulfonyl) Polyglutamine Aggregation Inhibitor III, C2-8 C2-8 (polyQ aggregation inhibitor C2-8) N-(4-Bromophenyl)-3-[[(4-bromophenyl)amino]sulfonyl]benzamide >=98% (HPLC), solid 300670-16-0