ChemicalBook >> CAS DataBase List >>2,4-Piperadinedione
2,4-Piperadinedione
- CAS No.
- 50607-30-2
- Chemical Name:
- 2,4-Piperadinedione
- Synonyms
- Piperidine-2,4-dione;PIPERIDIN-2,4-DIONE;2,4-Piperidinedione;2,4-PIPERADINEDIONE;2,4-Dioxopiperidine;2,4-PiperadinedioneE;2,4-Diketopiperidine;2,4-Piperidinedione>Piperidine-2,4-dione 97%;2,4-Piperidinedione, 95+%
- CBNumber:
- CB3511804
- Molecular Formula:
- C5H7NO2
- Molecular Weight:
- 113.11
- MDL Number:
- MFCD08704814
- MOL File:
- 50607-30-2.mol
- MSDS File:
- SDS
Last updated:2024-09-13 19:17:52
| Melting point | 98.0 to 102.0 °C |
|---|---|
| Boiling point | 362.1±35.0 °C(Predicted) |
| Density | 1.184±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | powder to crystal |
| pka | 12.00±0.70(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C5H7NO2/c7-4-1-2-6-5(8)3-4/h1-3H2,(H,6,8) |
| InChIKey | RDNZDMDLRIQQAX-UHFFFAOYSA-N |
| SMILES | N1CCC(=O)CC1=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H317-H319-H335 |
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38-43 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 3335 |
| WGK Germany | 3 |
| HS Code | 2933790090 |
2,4-Piperadinedione price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 759368 | 2,4-Piperidinedione 97% | 50607-30-2 | 250mg | $26.36 | 2024-03-01 | Buy |
| TCI Chemical | P2296 | 2,4-Piperidinedione >98.0%(GC)(T) | 50607-30-2 | 200mg | $18 | 2024-03-01 | Buy |
| TCI Chemical | P2296 | 2,4-Piperidinedione >98.0%(GC)(T) | 50607-30-2 | 1g | $59 | 2024-03-01 | Buy |
| TRC | P480020 | 2,4-Piperidinedione | 50607-30-2 | 5g | $165 | 2021-12-16 | Buy |
| TRC | P480020 | 2,4-Piperidinedione | 50607-30-2 | 2.5g | $120 | 2021-12-16 | Buy |
2,4-Piperadinedione Chemical Properties,Uses,Production
Description
2,4-Piperidinedione is an important piperidine ring-containing intermediate, and its 2,4-piperidinedione, as a characteristic fragment, is widely used as an intermediate in the synthesis of ibrutinib and paliperidone drugs.
Chemical Properties
White to light yellow solid
Uses
2,4-Piperidinedione is a reactant in the synthesis of 1,4-dihydropyridines as TGFβ/Smad inhibitors.
Preparation
The synthesis of 2,4-Piperidinedione involved dissolving 400 mg (2.34 mmol, 1.00 eq.) of Methyl 2,4-dioxo-piperidine-3-carboxylate in a mixture of acetonitrile (20 mL) and water (0.2 mL). The solution was then heated to approximately 86° C. and maintained at this temperature for around 4 hours. After completion of the reaction, the solvent was removed under vacuum, leaving behind a residue of 2,4-Piperidinedione. This residue was further purified using silica gel column chromatography with a mobile phase consisting of dichloromethane and methanol in a ratio of 100:1. The target product, 2,4-Piperidinedione, was obtained as a white solid, with a yield of 27%, corresponding to 70 mg.
2,4-Piperadinedione Preparation Products And Raw materials
Global( 243)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 17322 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20287 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18777 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 802 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
| Nanjing Baifuli Technology Co., Ltd. | +86-15335185688 | sales@unisyn.cn | CHINA | 332 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 2,4-Piperadinedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-02 | Piperidine-2,4-dione
50607-30-2
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2019-07-06 | 2,4-Piperadinedione
50607-30-2
|
US $1.00 / KG | 1KG | 99% | Customized | Career Henan Chemical Co | |
 |
2019-07-06 | 2,4-PiperadinedioneE
50607-30-2
|
US $1.00 / KG | 1KG | 97% | 200KG | Career Henan Chemical Co |
-
- Piperidine-2,4-dione
50607-30-2
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 2,4-Piperadinedione
50607-30-2
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
-
- 2,4-PiperadinedioneE
50607-30-2
- US $1.00 / KG
- 97%
- Career Henan Chemical Co
50607-30-2(2,4-Piperadinedione)Related Search:
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1of4
piperidine-2,4-dione, dihydropyridine-4,6-dione, 2,4-dioxopiperidine, 2,4-piperidinedione, piperidin-2,4-dione, 2,4-diketopiperidine, Piperidine-2,4-dione
2,4-PIPERADINEDIONE
2,4-Piperidinedione
dihydropyridine-4,6-dione
2,4-Dioxopiperidine
2,4-Piperidinedione, 95+%
2,4-Diketopiperidine
2,4-PiperadinedioneE
Piperidine-2,4-dione 97%
2,4-Piperidinedione>
2,4-Piperidinedione,Piperidine-2,4-dione
Piperidine-2,4-dione
PIPERIDIN-2,4-DIONE
2,4-Piperidinedione (9CI, ACI)
50607-30-2
Pharmaceutical intermediate
Heterocycles series