7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one structure

CAS No.: 2056122-65-5

Chemical Name:: 7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one

Synonyms: 7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one;Thieno[3,2-b]pyridin-5(4H)-one, 7-amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-

CBNumber:: CB35864433

Molecular Formula:: C19H20N6OS

Molecular Weight:: 380.47

MDL Number:

MOL File:: 2056122-65-5.mol

Last updated:2023-05-04 15:16:10

Request For Quotation

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Properties

Density	1.418±0.06 g/cm3(Predicted)
pka	10.67±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H335-H319-H315
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Chemical Properties,Uses,Production

Uses

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one is a HPK1 kinase inhibitor and has been shown to have in vivo antitumor activity. HPK1 kinase has been identified as a novel drug target for antitumor immunotherapy, as this kinase is involved in the extracellular-signaling pathways that inhibit the T-cell immuno antitumor response.

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai meikai technology co., ltd	021-18721550-091 18721550091	yangdong@pharma.com	China	4123	58

Supplier	Advantage
Shanghai meikai technology co., ltd	58

7-Amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-thieno[3,2-b]pyridin-5(4H)-one Thieno[3,2-b]pyridin-5(4H)-one, 7-amino-6-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]- 2056122-65-5