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Cefcapene pivoxil

Cefcapene pivoxil structure

CAS No.: 105889-45-0

Chemical Name:: Cefcapene pivoxil

Synonyms: Fumax;S-1108;Flumax;Cefcapene Piroxil;CEFCAPENE PIVOXIL;Cefcapene Impurity 3;Cefcapene pivoxil USP/EP/BP;Cefcapene Pivoxil Impurities;Cefcapene Pivoxil See C242555;Cefcapene pivoxil Impurity 13

CBNumber:: CB3680908

Molecular Formula:: C23H29N5O8S2

Molecular Weight:: 567.64

MDL Number:: MFCD00870176

MOL File:: 105889-45-0.mol

Last updated:2023-04-23 13:52:06

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Cefcapene pivoxil Properties

Melting point	158-164°C
Boiling point	888.4±65.0 °C(Predicted)
Density	1.47±0.1 g/cm3(Predicted)
solubility	DMSO, Water( warm)
form	Solid
pka	11.33±0.60(Predicted)
color	Off-White
FDA UNII	8I8MJ56XFQ

Cefcapene pivoxil price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C242550	CefcapenePivoxil	105889-45-0	10mg	$155	2021-12-16	Buy
Biosynth Carbosynth	FC37919	Cefcapene pivoxil 722ug/mg	105889-45-0	25mg	$167.5	2021-12-16	Buy
AK Scientific	G657	Cefcapenepivoxil	105889-45-0	25mg	$98	2021-12-16	Buy
Biosynth Carbosynth	FC37919	Cefcapene pivoxil 722ug/mg	105889-45-0	10mg	$104.7	2021-12-16	Buy
Biosynth Carbosynth	FC37919	Cefcapene pivoxil 722ug/mg	105889-45-0	50mg	$268	2021-12-16	Buy

Product number	Packaging	Price	Buy
C242550	10mg	$155	Buy
FC37919	25mg	$167.5	Buy
G657	25mg	$98	Buy
FC37919	10mg	$104.7	Buy
FC37919	50mg	$268	Buy

Cefcapene pivoxil Chemical Properties,Uses,Production

Description

Flomox was launched in Japan as an orally active cephalosporin for respiratory and urinary tract infections, heptatic infections, ophthalmological and otorhinolarynological infections, skinkoft tissue infections, and for use in gynacology, dentistry and oral surgery. It can be prepared by condesation of 2(Z)-(2-(t-butoxycarbonylamino) thiazol-4-yl)-2-pentenoic acid with 7-amino-3-(carbanoyloxymethyl)- 3-cephem-4-carboxylic acid pivaloyl methyl ester followed by deprotection. Flomox is highly active against a wide variety of Gram-positive and Gram-negative bacteria, except for several strains such as Pseudomonas aeruginosa and enterococci, by acting as a cell wall synthesis inhibitor (β-lactamase stability against TEM-1 type β-lactamases) and is more effective than cefaclor and cefdinir. Absorption is improved by the pivaloyloxymethyl ester group which is easily lost by deesterification during GI absorption to produce the biologically active form. The pivalic acid generated quickly conjugates with carnitine and is excreted in the urine. The drop in plasma levels of carnitine was dose dependent and returned to normal levels upon termination of treatment.

Chemical Properties

Off-White Solid

Originator

Shionogi (Japan)

Uses

Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, Cefcapene.

brand name

Flomox

Cefcapene pivoxil Preparation Products And Raw materials

Raw materials

Phosphoric acid Anisole Trifluoroacetic acid Methanesulfonyl chloride Iodomethane

Preparation Products

Cefcapene pivoxil Suppliers

Global( 108)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8618959220845	sales@amoychem.com	China	6383	58
Shanghai Longyu Biotechnology Co., Ltd.	+8619521488211	info@longyupharma.com	China	2541	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17365	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	7724	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15352	58
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	gksales1@gk-bio.com	China	9314	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Xiamen AmoyChem Co., Ltd	58
Shanghai Longyu Biotechnology Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
SIMAGCHEM CORP	58
Shaanxi Dideu Medichem Co. Ltd	58
AFINE CHEMICALS LIMITED	58
Baoji Guokang Bio-Technology Co., Ltd.	58

View Lastest Price from Cefcapene pivoxil manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-10	Cefcapene Pivoxil 105889-45-0	US $0.00-0.00 / mg	10mg	90%+	10g	Guangzhou PI PI BIOTECH INC
2024-04-10	Cefcapene Pivoxil Impurities 105889-45-0	US $0.00-0.00 / mg	10mg	90%+	10g	Guangzhou PI PI BIOTECH INC
2021-07-10	Cefcapene pivoxil 105889-45-0	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Cefcapene Pivoxil
105889-45-0
US $0.00-0.00 / mg
90%+
Guangzhou PI PI BIOTECH INC

Cefcapene Pivoxil Impurities
105889-45-0
US $0.00-0.00 / mg
90%+
Guangzhou PI PI BIOTECH INC

Cefcapene pivoxil
105889-45-0
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

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METSULFURON METHYL Methyl Methyl bromide

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(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester Fumax S-1108 Cefcapene Piroxil Flumax CEFCAPENE PIVOXIL Cefcapene Pivoxil See C242555 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(2,2-diMethyl-1-oxopropoxy)Methyl ester, (6R,7R)- (6R,7R)-7-[[(Z)-2-(2-amino-4-thiazolyl)-1-oxopent-2-enyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester Cefcapene Impurity 3 (6R,7R)-(pivaloyloxy)methyl7-((Z)-2-(2-aminothiazol-4-yl)pent-2-enamido)-3-((carbamoyloxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Cefcapene pivoxil USP/EP/BP Cefcapene Pivoxil Impurities Cefditoren pivoxilQ: What is Cefditoren pivoxil Q: What is the CAS Number of Cefditoren pivoxil Q: What is the storage condition of Cefditoren pivoxil Q: What are the applications of Cefditoren pivoxil 105889-45-0 Cefcapene pivoxil Cefcapene pivoxil Impurity 13 Cefcapene pivoxil Powder USP Standard 105889-45-0 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Heterocycles Metabolites & Impurities Sulfur & Selenium Compounds Pharmaceutical intermediate