Tetrahydro-4H-pyran-4-one
- CAS No.
- 29943-42-8
- Chemical Name:
- Tetrahydro-4H-pyran-4-one
- Synonyms
- dihydro-2H-pyran-4(3H)-one;Oxan-4-one;TETRAHYDROPYRAN-4-ONE;4-THP;4-OXOTETRAHYDROPYRAN;4H-Pyran-4-one, tetrahydro-;EOS-60523;1KG,10KG,25KG;TETRAHYDRO-GAMM;4-Oxacyclohexanone
- CBNumber:
- CB3703050
- Molecular Formula:
- C5H8O2
- Molecular Weight:
- 100.12
- MDL Number:
- MFCD00006581
- MOL File:
- 29943-42-8.mol
- MSDS File:
- SDS
| Boiling point | 166-166.5 °C (lit.) |
|---|---|
| Density | 1.084 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 134 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Liquid |
| color | Clear colorless to pale yellow |
| Water Solubility | MISCIBLE |
| BRN | 106463 |
| InChIKey | JMJRYTGVHCAYCT-UHFFFAOYSA-N |
| CAS DataBase Reference | 29943-42-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 4H-Pyran-4-one, tetrahydro-(29943-42-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P210 | |||||||||
| Hazard Codes | Xi,F | |||||||||
| Risk Statements | 10-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| RIDADR | UN 1224 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| Hazard Note | Keep Cold/Flammable/Irritant | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29329995 | |||||||||
| NFPA 704 |
|
Tetrahydro-4H-pyran-4-one price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 198242 | Tetrahydro-4H-pyran-4-one 99% | 29943-42-8 | 1g | $41.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 198242 | Tetrahydro-4H-pyran-4-one 99% | 29943-42-8 | 5g | $135 | 2024-03-01 | Buy |
| TCI Chemical | T1806 | Tetrahydro-4H-pyran-4-one >95.0%(GC) | 29943-42-8 | 1g | $37 | 2024-03-01 | Buy |
| TCI Chemical | T1806 | Tetrahydro-4H-pyran-4-one >95.0%(GC) | 29943-42-8 | 5g | $104 | 2024-03-01 | Buy |
| Alfa Aesar | A19010 | Tetrahydro-4H-pyran-4-one 98% | 29943-42-8 | 1g | $41.65 | 2024-03-01 | Buy |
Tetrahydro-4H-pyran-4-one Chemical Properties,Uses,Production
Description
Tetrahydro-4H-pyran-4-one is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes.
The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. Tetrahydro-4H-pyran-4-one is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3.
Application
Tetrahydro-4-pyrone is used in organic synthesis as a building block for more complex chemical structures because it participates in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid and it undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of penicillins and in a ring of vitamin D3. Additionally, tetrahydro-4-pyrone is used as solvents in some reactions.
Chemical Properties
colorless to light yellow liquid
Uses
Tetrahydro-4-pyrone is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions.
Purification Methods
Purify the pyrone by repeated distillation, preferably in a vacuum. [Baker J Chem Soc 296 1944, IR: Olsen & Bredoch Chem Ber 91 1589 1958.] The oxime has m 87-88o and b 110-111o/13mm [Cornubert et al. Bull Soc Chim Fr 36 1950]. The 4-nitrophenylhydrazone forms orange-brown needles from EtOH, m 186o [Cawley & Plant J Chem Soc 1214 1938]. [Beilstein 17 I 131, 17 II 287, 17 III/IV 4171, 17/9 V 21.]
Tetrahydro-4H-pyran-4-one Preparation Products And Raw materials
Raw materials
1of5
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Ryan Pharmachem Technology Co.,Ltd. | +86-512-68780025 +8618962125825 | sales@ryanchem.com | China | 136 | 58 |
| BTC pharm India | +918790379245 | banny.janga@btcpharm.com | India | 1262 | 58 |
| Shanghai Yongzeng Technology Co.,Ltd | +86-021-65281118 +86-13818947575 | sales@yongzchem.com | China | 137 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18154 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Hebei Ganmiao New material Technology Co., LTD | +86-17332992504 +86-17332992504 | sales8@hbganmiao.com | China | 299 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
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View Lastest Price from Tetrahydro-4H-pyran-4-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | Tetrahydro-4H-pyran-4-one
29943-42-8
|
US $65.00 / kg | 1kg | 99% | 5000kg/week | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-21 | Tetrahydro-4H-pyran-4-one
29943-42-8
|
US $0.00 / KG | 1KG | 99%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-04 | Tetrahydro-4H-pyran-4-One
29943-42-8
|
US $370.00 / kg | 1kg | 99%min | 100kgs | Shanghai Yongzeng Technology Co.,Ltd |
-
- Tetrahydro-4H-pyran-4-one
29943-42-8
- US $65.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Tetrahydro-4H-pyran-4-one
29943-42-8
- US $0.00 / KG
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Tetrahydro-4H-pyran-4-One
29943-42-8
- US $370.00 / kg
- 99%min
- Shanghai Yongzeng Technology Co.,Ltd
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