ASTRAGALIN
- CAS No.
- 480-10-4
- Chemical Name:
- ASTRAGALIN
- Synonyms
- KAEMPFEROL-3-O-GLUCOSIDE;astragaline;Kaempferol 3-O-β-D-glucopyranoside;KAEMPFEROL-3-GLUCOSIDE;k5;Astragalin ,98%;kaempferol 3-O-beta-D-glucoside;Kaempferol 3-β-D-glucopyranoside;KAEMPFEROL-3-O-BETA-D-GLUCOPYRANOSIDE;5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
- CBNumber:
- CB3732744
- Molecular Formula:
- C21H20O11
- Molecular Weight:
- 448.38
- MDL Number:
- MFCD00075932
- MOL File:
- 480-10-4.mol
| Melting point | 223-229°C |
|---|---|
| Boiling point | 823.2±65.0 °C(Predicted) |
| Density | 1.79±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml |
| pka | 6.20±0.40(Predicted) |
| form | Solid |
| color | Yellow |
| biological source | mouse |
| InChIKey | JPUKWEQWGBDDQB-QSOFNFLRSA-N |
| LogP | 1.950 (est) |
| CAS DataBase Reference | 480-10-4(CAS DataBase Reference) |
| FDA UNII | APM8UQ3Z9O |
| UNSPSC Code | 85151701 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Safety Statements | 22 |
| WGK Germany | 3 |
| RTECS | DJ3080000 |
| HS Code | 29389090 |
ASTRAGALIN price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB5300267 | Monoclonal Anti-Cytokeratin 5 antibody produced in mouse clone 2C2, purified immunoglobulin, buffered aqueous solution | 480-10-4 | 100μg | $524 | 2024-03-01 | Buy |
| Sigma-Aldrich | 04500585 | Kaempferol 3-glucoside primary pharmaceutical reference standard | 480-10-4 | 10mg | $482 | 2024-03-01 | Buy |
| Sigma-Aldrich | SAB5300265 | Monoclonal Anti-Cytokeratin 5 antibody produced in mouse clone 1E1, ascites fluid | 480-10-4 | 100μL | $466 | 2022-05-15 | Buy |
| Sigma-Aldrich | 68437 | Kaempferol 3-glucoside analytical standard | 480-10-4 | 5MG | $568 | 2022-05-15 | Buy |
| Cayman Chemical | 25060 | Kaempferol 3-glucoside ≥98% | 480-10-4 | 5mg | $117 | 2024-03-01 | Buy |
ASTRAGALIN Chemical Properties,Uses,Production
Overview
Astragalin is a chemical compound. It can be isolated from Phytolacca americana (the American pokeweed) or in the methanolic extract of fronds of the fern Phegopteris connectilis.t is also found in wine.
source
Astragalin belongs to the class of organic compounds known as flavonoid-3-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C3-position. Astragalin exists as a solid, slightly soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, astragalin is primarily located in the cytoplasm. Astragalin can be converted into astragalin heptaacetate and 2''-acetylastragalin. Outside of the human body, astragalin can be found in a number of food items such as tamarind, american cranberry, chickpea, and bilberry. This makes astragalin a potential biomarker for the consumption of these food products.
Chemical Properties
Yellow solid powder
Uses
Astragaline is found in Erica multiflora leaf extract, which is used for mitigating high-?fat and high-?fructose diet (HFFD)?-?induced metabolic syndrome.
Definition
ChEBI: A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage.
Biological Activity
Similar kaempferol glycosides reduce food intake and corresponding weight gain in Wistar rats.The glucoside was not tested.
in vivo
Astragalin (25, 50, and 75 mg/kg; p.o.; once every two days; 25 d) reduces the tumor volumes, tumor weight and tumor formation rates and decreases expression of p-NFκB and p-iκκα in nude mouse model?with human colon cancer[1].
| Animal Model: | Male BALB/c nude mice (4-week-old) with HCT116 cells (s.c.)[1] |
| Dosage: | 0 mg/kg, 25 mg/kg, 50 mg/kg, 75 mg/kg |
| Administration: | Oral gavage; once every two days; for 25 days |
| Result: | Resulted tumor inhibition rates of 17.43%, 34.89% (p?< 0.01), and 67.06% with 25 mg/kg, 50 mg/kg, 75 mg/kg dose administration. Showed no effect on mouse weight. |
IC 50
p65
ASTRAGALIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12800 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
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View Lastest Price from ASTRAGALIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-29 | Astragalin
480-10-4
|
US $30.00-83.00 / mg | 99.91% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-23 | ASTRAGALIN
480-10-4
|
US $0.00 / KG | 1KG | 99% | 100 MT | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-03-21 | ASTRAGALIN
480-10-4
|
US $10.00 / KG | 1KG | 99% | 500000KG | Hebei Mujin Biotechnology Co.,Ltd |
-
- Astragalin
480-10-4
- US $30.00-83.00 / mg
- 99.91%
- TargetMol Chemicals Inc.
-
- ASTRAGALIN
480-10-4
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- ASTRAGALIN
480-10-4
- US $10.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd