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THIAMINE HYDROCHLORIDE

THIAMINE HYDROCHLORIDE structure

CAS No.: 70-16-6

Chemical Name:: THIAMINE HYDROCHLORIDE

Synonyms: THIAMINE;THIAMINE HCL;VITAMIN B1 HCL;VIT B1;Thiamine ion;THIAMIN HYDROCHLORIDE;ANEURIN;FEMA 3322;ANEURIN HCL;ANEURINE HCL

CBNumber:: CB3741700

Molecular Formula:: C12H17N4OS+

Molecular Weight:: 265.35

MDL Number:: MFCD00012780

MOL File:: 70-16-6.mol

Last updated:2024-08-21 22:41:43

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THIAMINE HYDROCHLORIDE Properties

Melting point	250 °C (dec.)(lit.)
storage temp.	2-8°C
solubility	H₂O: 0.1 g/mL at 20 °C, clear, colorless
BCS Class	3
FDA UNII	4ABT0J945J

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	1
RTECS	XI7350000
F	3-8-10
HS Code	29362200

THIAMINE HYDROCHLORIDE Chemical Properties,Uses,Production

Physical properties

Free thiamin is unstable because of its quaternary nitrogen; in water, it is cleaved to the thiol form. For this reason, the hydrochloride and mononitrate forms are used in commerce. Thiamin hydrochloride (actually, thiamin chloride hydrochloride) is a colorless crystal that is very soluble in water (1 g/ml, thus making it a very suitable form for parenteral administration), soluble in methanol and glycerol, but practi cally insoluble in acetone, ether, chloroform, and benzene. The mononitrate form is more stable than the hydrochloride form, but it is less soluble in water. It is used in food/feed supplementation and in dry pharmaceutical preparations. Free thiamin is easily oxidized to thiamin disulfide and other derivatives, including thiochrome, a yellow biologically inactive product with strong blue fluorescence that can be used for the quantitative determination of thiamin. Its metabolically active form is thia min diphosphate, also called thiamin pyrophosphate.

Definition

ChEBI: Thiamine(1+) is a primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a primary alcohol and a vitamin B1. It is a conjugate base of a thiamine(2+).

THIAMINE HYDROCHLORIDE synthesis

Synthesis of THIAMINE HYDROCHLORIDE from 4-Amino-5-aminomethyl-2-methylpyrimidine

THIAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Thiamine Impurity 5 5-Pyrimidineaceticacid, 3,4-dihydro-2-methyl-4-oxo-, ethyl ester 5-Pyrimidineacetamide, 4-amino-2-methyl- Pyrimidine, 4-chloro-5-(ethoxymethyl)-2-methyl- 4-Pyrimidinamine, 5-(bromomethyl)-2-methyl- (9CI)

4-Amino-5-aminomethyl-2-methylpyrimidine THIOTHIAMINE 5-ethoxymethyl-2-methylpyrimidin-4-ylamine NSC 51127 5-(2-Hydroxyethyl)-4-methylthiazole

Pyruvic acid

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Preparation Products

THIAMINE HYDROCHLORIDE Suppliers

Global( 49)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12834	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Hebei Kingfiner Technology Development Co.Ltd	+86-15532196582 +86-15373005021	lisa@kingfinertech.com	China	3009	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	615	58
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1001	58
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8807	58
Hebei Binshare New Material Co. Ltd	+8618633865755	china01@hbbinshare.com	CHINA	955	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2783	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30238	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Kingfiner Technology Development Co.Ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
Nanjing Finetech Chemical Co., Ltd.	55
Shanxi Naipu Import and Export Co.,Ltd	58
Hebei Weibang Biotechnology Co., Ltd	58
Hebei Binshare New Material Co. Ltd	58
Longyan Tianhua Biological Technology Co., Ltd	58
Career Henan Chemica Co	58

View Lastest Price from THIAMINE HYDROCHLORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-10-22	THIAMINE HYDROCHLORIDE 70-16-6	US $1.00 / g	1g	85.0-99.8%	20 tons	Career Henan Chemica Co
2024-10-11	Thiamine 70-16-6	US $10.00 / kg	1kg	98%	10 ton	Hebei Chuanghai Biotechnology Co,.LTD
2024-09-25	THIAMINE HYDROCHLORIDE 70-16-6	US $0.00-0.00 / kg	1kg	99%	500kg	Wuhan Senwayer Century Chemical Co.,Ltd

THIAMINE HYDROCHLORIDE
70-16-6
US $1.00 / g
85.0-99.8%
Career Henan Chemica Co

Thiamine
70-16-6
US $10.00 / kg
98%
Hebei Chuanghai Biotechnology Co,.LTD

THIAMINE HYDROCHLORIDE
70-16-6
US $0.00-0.00 / kg
99%
Wuhan Senwayer Century Chemical Co.,Ltd

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TIMTEC-BB SBB001377 THIAMIO HYDROCHLORIDUM THIAMINIUM CHLORIDE HYDROCHLORIDE THIAMINIUM DICHLORIDE THIAMINE CHLORIDE HYDROCHLORIDE B1-THIAMINE HYDROCHLORIDE FEMA 3322 LABOTEST-BB LT00455558 ANEURIN ANEURIN HCL 3-(4-AMINO-2-METHYLPYRIMIDYL-5-METHYL)-4-METHYL-5-(B-HYDROXYETHYL)THIAZOLIUM CHLORIDE HYDROCHLORIDE ANEURINE HCL 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium thiamine(1+) Thiamine vb 1 Thiamine Hydrochloride CAS NO.70-16-6 Vitamin B1 THIAMINE HYDROCHLORIDE THIAMINE HYDROCHLORIDE Antiberiberi THIAMIN HYDROCHLORIDE THIAMINE THIAMINE HCL VIT B1 VITAMIN B1 HCL Thiamine ion 70-16-6 Asymmetric Synthesis Chiral Building Blocks Complex Molecules