REC BETA-ECGF (HUMAN)
- CAS No.
- 105843-51-4
- Chemical Name:
- REC BETA-ECGF (HUMAN)
- Synonyms
- FGFA;ECGFA;ECGFB;β-ECGF;GLIO703;BETA-ECGF;FGF-alpha;RH-BETA-ECGF;β-ECGF, ECGS;HUMAN BETA-ECGF
- CBNumber:
- CB3768477
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131012
- MOL File:
- Mol file
REC BETA-ECGF (HUMAN) price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E1388 | β-Endothelial Cell Growth Factor human β-ECGF, recombinant, expressed in E. coli, suitable for cell culture | 105843-51-4 | 25μg | $389 | 2024-03-01 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| E1388 | 25μg | $389 | Buy |
REC BETA-ECGF (HUMAN) Chemical Properties,Uses,Production
Uses
β-Endothelial Cell Growth Factor human has been used:
- in cell death assay
- in endothelial cell culture
- in human umbilical vascular endothelial cell (HUVEC) culture
General Description
The β-endothelial cell growth factor (b-ECGF) gene encodes an angiogenic factor, and is mapped to human chromosome 11q13.1. Recombinant, human b-endothelial cell growth factor (b-ECGF) is a 14 amino acid N-terminal extension of acidic fibroblast growth factor. It is expressed in Escherichia coli. The 154 amino acid recombinant protein, generated after removal of the initiation methionine, has a predicted molecular mass of about 17 kDa.
Biochem/physiol Actions
β-Endothelial cell growth factor (β-ECGF) is a potent endothelial cell mitogen and its mitogenic activity is potentiated by heparin. β-ECGF stimulates the growth of quiescent HUVEC cells in culture. β-ECGF is associated with lipid and glucose metabolism. This growth factor induces neovascularization in disease conditions. Upregulation of β-ECGF is observed in diabetic retinopathy, and polycystic ovary syndrome. It is also associated with tumor proliferation and invasion. β-ECGF increases fatty acid transport proteins expression to improve endothelial mediated lipid transpor.
REC BETA-ECGF (HUMAN) Preparation Products And Raw materials
Raw materials
Preparation Products
REC BETA-ECGF (HUMAN) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Duling International Trade Co. LTD | +8617333973358 | sales01@hbduling.cn | China | 15437 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Hebei Duling International Trade Co. LTD | 58 |
| Sigma-Aldrich | 80 |
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