3-Methylseleno-L-alanine Hydrochloride
- CAS No.
- 863394-07-4
- Chemical Name:
- 3-Methylseleno-L-alanine Hydrochloride
- Synonyms
- 3-(Methylseleno)-Ala-OH.HCl;Se-Methylselenocysteine HCL;3-Methylseleno-L-alanine Hydrochloride;Se-
(Methyl) selenocysteine hydrochloride;Se-(Methyl)selenocysteine hydrochloride >=95% (TLC);(R)-2-aMino-3-(Methylselanyl)propanoic acid hydrochloride
- CBNumber:
- CB3854480
- Molecular Formula:
- C4H10ClNO2Se
- Molecular Weight:
- 218.5407
- MDL Number:
- MFCD03412450
- MOL File:
- 863394-07-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H331-H373-H410 | |||||||||
| Precautionary statements | P260-P264-P273-P301+P310-P304+P340+P311-P314 | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 23/25-33-50/53 | |||||||||
| Safety Statements | 20/21-28-45-60-61 | |||||||||
| RIDADR | UN 3283 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
3-Methylseleno-L-alanine Hydrochloride price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M6680 | Se-(Methyl)selenocysteine hydrochloride ≥95% (TLC) | 863394-07-4 | 100mg | $298 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | AAA0003372 | SE-(METHYL)SELENOCYSTEINE HYDROCHLORIDE 95.00% | 863394-07-4 | 100MG | $745.24 | 2021-12-16 | Buy |
| ChemPep | 350105 | 3-(Methylseleno)-L-alanine•HCl | 863394-07-4 | 1g | $1076 | 2021-12-16 | Buy |
| ChemPep | 350105 | 3-(Methylseleno)-L-alanine•HCl | 863394-07-4 | 5g | $2959 | 2021-12-16 | Buy |
| Crysdot | CD21001893 | 3-(Methylseleno)-Ala-OH.HCl 97% | 863394-07-4 | 1g | $1320 | 2021-12-16 | Buy |
3-Methylseleno-L-alanine Hydrochloride Chemical Properties,Uses,Production
Uses
Se-(Methyl) selenocysteine hydrochloride has been used as a standard in fluorescence-XANES (X-ray absorption near-edge spectroscopy) imaging.
General Description
Selenium (Se)-(Methyl) selenocysteine (MeSeCys) is a methylated product of selenocysteine, this reaction is catalyzed by selenocysteine methyltransferase (SMT) in Astragalus bisulcatus.
Biochem/physiol Actions
Selenium (Se)-(Methyl) selenocysteine functions as a potent chemotherapeutic agent for human breast cancer. Enhanced production of methlylselenol from L-Se-methylselenocysteine in vivo alters redox status of cells and oxidatively triggers cellular apoptosis. It is implicated in inhibition of mammary tumor formation in rats.
in vivo
Se-Methylselenocysteine hydrochloride (0.2?mg/mouse; p.o.; daily for 14 days) potentiates the antitumour activity of CDDP and Cyclophosphamide in nude mice bearing human FaDu and A253 head and neck xenografts[2].
?
Alzheimer's disease (AD) mice are treats with Se-Methylselenocysteine hydrochloride (0.75 mg/kg BW per day) in their drinking water for 10 months. Se-Methylselenocysteine hydrochloride reduces oxidative stress and neuro-inflammation; Se-Methylselenocysteine hydrochloride modulates the distribution and levels of several metal ions; Se-Methylselenocysteine hydrochloride decreases amyloid-β peptide (Aβ) generation by inhibiting the expression of its precursor protein APP and β-secretase (BACE1), and attenuates tau hyperphosphorylation and neurofibrillary tangles (NFT) formation via promoting protein phosphatase 2A (PP2A) activity, thereby preserving synaptic proteins and neuron activities and finally improving spatial learning and memory deficits in AD model mice[3].
3-Methylseleno-L-alanine Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Adachibio Inc. | +8108027837258 | sales@adachi-bio.com | China | 992 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 970 | 59 |
| ChemPep, Inc. | +1 (888) 615-9178 / (561) 791-8787 | service@chempep.com | United States | 2138 | 57 |
| Okeanos Tech Co,. Ltd. | 010-62651721 18610486005 | minghui.yu@okeanos.com.cn | China | 495 | 60 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4720 | 55 |
| Supplier | Advantage |
|---|---|
| Adachibio Inc. | 58 |
| BOC Sciences | 58 |
| Nextpeptide Inc | 58 |
| LEAP CHEM CO., LTD. | 58 |
| Aladdin Scientific | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 62 |
| Alabiochem Tech.Co., Ltd. | 59 |
| ChemPep, Inc. | 57 |
| Okeanos Tech Co,. Ltd. | 60 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 55 |
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