1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine
- CAS No.
- 120014-07-5
- Chemical Name:
- 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine
- Synonyms
- Donepezil-013;Donepezil-013-Z;Dehydro Donepezi;Dehydro Donepezil;Donepezil USP RC A;Donepezil Impurity O;Donepezil Impurity 17;Donepezil related compound;1-Benzyl-4-(5,6-dimethoxy-1-ox;2-[(1-Benzylpiperidin-4-yl)methylen
- CBNumber:
- CB3854945
- Molecular Formula:
- C24H27NO3
- Molecular Weight:
- 377.48
- MDL Number:
- MFCD08693144
- MOL File:
- 120014-07-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319 |
Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
HS Code | 2933399990 |
1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine price More Price(22)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
AK Scientific | J11663 | Donepezilrelatedcompound(E/Zmixture) | 120014-07-5 | 100mg | $49 | 2021-12-16 | Buy |
Oakwood | 036506 | 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine 97% | 120014-07-5 | 1g | $55 | 2021-12-16 | Buy |
Biosynth Carbosynth | IB18353 | 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine | 120014-07-5 | 100mg | $60 | 2021-12-16 | Buy |
Biosynth Carbosynth | IB18353 | 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piperidine | 120014-07-5 | 250mg | $100 | 2021-12-16 | Buy |
Apolloscientific | OR61173 | 2-[(1-Benzylpiperidin-4-yl)methylidene]-2,3-dihydro-5,6-dimethoxy-1H-inden-1-one 97% | 120014-07-5 | 5g | $137 | 2021-12-16 | Buy |
1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine Chemical Properties,Uses,Production
Synthesis
A solution of 5,6-dimethoxy-indanone (19 g, 0.10 mol) in methanol (8 mL) is stirred under inert
atmosphere at room temperature. Slowly add NaOH flakes
(12.8 g, 0.32 mol) followed by N-benzyl-piperidine-4-carboxaldehyde (20.2 g, 0.10 mol) to the reaction mixture. The
mixture was stirred at room temperature for 3 h and progress
of the reaction was monitored by TLC (hexane:ethyl acetate;
1:1). Once the reaction is complete, the solid formed was
filtered, washed with 5 % acetic acid and then with methanol
and dried. The obtained solid (34 g) was taken into a round
bottom flask and refluxed with DMF (50 mL). Gradually cooled
to room temperature and stirred for 2 h, filtered the solid
formed, wash with chilled methanol to afford a pale yellow
crystalline solid 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine (32.0 g, 84 %); m.p.: 175-177 °C.
Uses
An impurity of Donepezil; an intermediate as an anti-Alzheimer agent.
Uses
An impurity of Donepezil (D531750); an intermediate as an anti-Alzheimer's agent.
1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10828 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35426 | 58 |
View Lastest Price from 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2020-01-03 | 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine
120014-07-5
|
US $1.00 / KG | 1KG | 99% | 10000KGS | Career Henan Chemical Co |
-
- 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine
120014-07-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co