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Benzyl nicotinate

CAS No.
94-44-0
Chemical Name:
Benzyl nicotinate
Synonyms
yansuanbianzhi;Benzylnicotinat;NICOTINIC ACID BENZYL ESTER;Pykaryl;Pycaril;RUBRIMENT;niacinbenzylester;BENZYL NICOTINATE;Niacin benzyl ester;BenzylNicotinate>
CBNumber:
CB9363852
Molecular Formula:
C13H11NO2
Molecular Weight:
213.23
MDL Number:
MFCD00023584
MOL File:
94-44-0.mol
MSDS File:
SDS
Last updated:2025-04-30 13:36:08

Benzyl nicotinate Properties

Melting point 24 °C (lit.)
Boiling point 177 °C/8 mmHg (lit.)
Density 1,1165 g/cm3
refractive index n20/D 1.570
Flash point 170°C
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form <24°C Solid,>24°C Liquid
pka 3.16±0.10(Predicted)
color Colourless to Light Beige
Merck 14,6526
BRN 159169
LogP 2.400
CAS DataBase Reference 94-44-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII S497LCF9C9
NIST Chemistry Reference Nicotinic acid, benzyl ester(94-44-0)
EPA Substance Registry System 3-Pyridinecarboxylic acid, phenylmethyl ester (94-44-0)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26
WGK Germany  2
RTECS  QT0850000
8
TSCA  Yes
HS Code  2933399990
NFPA 704
1
2 0

Benzyl nicotinate price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 72351 Benzyl nicotinate ≥98.0% (GC) 94-44-0 100ml $129 2024-03-01 Buy
Sigma-Aldrich 72351 Benzyl nicotinate ≥98.0% (GC) 94-44-0 500ml $536 2024-03-01 Buy
TCI Chemical N0083 Benzyl Nicotinate >98.0%(GC) 94-44-0 25g $29 2024-03-01 Buy
TCI Chemical N0083 Benzyl Nicotinate >98.0%(GC) 94-44-0 100g $98 2021-12-16 Buy
Alfa Aesar A18505 Benzyl nicotinate, 99% 94-44-0 50g $57.4 2024-03-01 Buy
Product number Packaging Price Buy
72351 100ml $129 Buy
72351 500ml $536 Buy
N0083 25g $29 Buy
N0083 100g $98 Buy
A18505 50g $57.4 Buy

Benzyl nicotinate Chemical Properties,Uses,Production

Chemical Properties

Benzyl nicotinate is a benzyl ester resulting from the formal condensation of the carboxy group of nicotinic acid with benzyl alcohol. It derives from a nicotinic acid. It is a vasodilator agent and is also generally used in cosmetics and drugs.It has been used as a rubefacient.
Benzyl nicotinate can be used for the synthesis of benzylpalladium complexes to be used as catalysts for the substitution of olefins with benzylic groups.

Uses

benzyl nicotinate can increase skin oxygenation—thanks to vasodilatation properties—and help stimulate the healing process of wounded skin. It is an ester form of niacin (vitamin B), benzyl alcohol, and nicotinic acid.

Uses

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Uses

Benzyl nicotinate can be used for the synthesis of benzylpalladium complexes to be used as catalysts for the substitution of olefins with benzylic groups.

Definition

ChEBI: A benzyl ester resulting from the formal condensation of the carboxy group of nicotinic acid with benzyl alcohol. It has been used as a rubefacient.

Synthesis Reference(s)

Synthetic Communications, 14, p. 515, 1984 DOI: 10.1080/00397918408059573

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Benzyl Nicotinate is a medication widely used as a vasodilator, that widens blood vessels. It basically oxygenates and flushes the skin′s capillaries.

Clinical Use

Benzyl nicotinate is used in combination with heparin in the treatment of inflammation of vein (thrombophlebitis), pain in dilated veins area, pains and cramps in the leg muscles, disturbances of lymph circulation, traffic and sports related injuries, postoperative and posttraumatic scars, non-joint rheumatism or soft tissue rheumatism.

Side effects

The common side-effects of Heparin+benzyl Nicotinate are skin irritation, redness, burning sensation, and itching. These side-effects are usually mild and temporary.

93-60-7
100-51-6
94-44-0
Synthesis of Benzyl nicotinate from Methyl nicotinate and Benzyl alcohol

Benzyl nicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 308)Suppliers
Supplier Tel Email Country ProdList Advantage
Fluoropharm Co., Ltd.
+86-0571-85586753 +86-13336034509 sales@fluoropharm.com China 1445 60
Henan Alfa Chemical Co., Ltd
+8615838112936 alfa10@alfachem.cn China 13194 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531157085 abby@chuanghaibio.com China 8808 58
Hebei Mujin Biotechnology Co.,Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12798 58
Hebei Yanxi Chemical Co., Ltd.
+8617531153977 allison@yan-xi.com China 5854 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5868 58
Anhui Yiao New Material Technology Co., Ltd
+86-18033737140 +86-17354101231 sales1@hbganmiao.com China 227 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 3005 58
airuikechemical co., ltd.
+86-18353166132 +86-18353166132 sales02@airuikechemical.com China 983 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 +86-16264648883 niki@zlchemi.com China 7245 58

View Lastest Price from Benzyl nicotinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Benzyl nicotinate pictures 2025-04-30 Benzyl nicotinate
94-44-0
US $29.00 / g 98.22% 10g TargetMol Chemicals Inc.
Benzyl Nicotinate pictures 2025-04-30 Benzyl Nicotinate
94-44-0
US $99.00-45.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co Ltd
Benzyl nicotinate pictures 2025-04-23 Benzyl nicotinate
94-44-0
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
  • Benzyl Nicotinate pictures
  • Benzyl Nicotinate
    94-44-0
  • US $99.00-45.00 / kg
  • 99%
  • Hebei Zhuanglai Chemical Trading Co Ltd
3-Pyridinecarboxylic acid, phenylmethyl ester 3-Pyridinecarboxylicacid,phenylmethylester Benzyl pyridine-3-carboxylate benzylpyridine-3-carboxylate Estru benzylowego kwasu nikotynowego estrubenzylowegokwasunikotynowego Niacin benzyl ester niacinbenzylester Pycaril Pykaryl Pyridine-3-carboxylic acid benzyl ester RUBRIMENT BENZYL NICOTINATE BenzylNicotinate,>98% 3-Pyridinecarboxylic acid benzyl ester Nicotinic acid benzyl nicotin benzyl ester phenylmethyl pyridine-3-carboxylate Nicotinic acid benzy Benzyl nicotinate >=98.0% (GC) Nicotinic acid benzyl este Nicotinic Acid Benzyl Ester (Benzyl Nicotinate) BenzylNicotinate> Benzyl nicotinate (JAN) Benzyl nicotinate ISO 9001:2015 REACH NICOTINIC ACID BENZYL ESTER Benzylnicotinat yansuanbianzhi 5-CHLORO-1,3-BENZODIOXOL-4-AMINE 379228-45-2 Mannose Impurity 25 Benzyl nicotinate, 10 mM in DMSO 94-44-0 99-44-0 Building Blocks C9 to C46 Pyridines Heterocyclic Building Blocks