anipamil
- CAS No.
- 83200-10-6
- Chemical Name:
- anipamil
- Synonyms
- anipamil;Anipamilum [Latin];anipamil USP/EP/BP;2-Dodecyl-5-[3-methoxyphenethyl(methyl)amino]-2-(3-methoxyphenyl)pentanenitrile;2-(3-methoxyphenyl)-2-[3-[2-(3-methoxyphenyl)ethyl-methylamino]propyl]tetradecanenitrile;Benzeneacetonitrile, α-dodecyl-3-methoxy-α-[3-[[2-(3-methoxyphenyl)ethyl]methylamino]propyl]-
- CBNumber:
- CB3884252
- Molecular Formula:
- C34H52N2O2
- Molecular Weight:
- 520.79
- MDL Number:
- MFCD00867066
- MOL File:
- 83200-10-6.mol
| storage temp. | Store at -20°C |
|---|---|
| solubility | Acetone (Slightly), Methanol (Slightly) |
| form | Thick Oil to Gel |
| color | Pale Yellow |
| FDA UNII | 9Y54WZV1CJ |
anipamil price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A672700 | Anipamil | 83200-10-6 | 10mg | $165 | 2021-12-16 | Buy |
| TRC | A672700 | Anipamil | 83200-10-6 | 100mg | $1320 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010715 | ANIPAMIL 95.00% | 83200-10-6 | 5MG | $503.47 | 2021-12-16 | Buy |
anipamil Chemical Properties,Uses,Production
Originator
Anipamil,Onbio Inc.
Uses
A long-acting analog of Verapamil (V125000) with antiarrhythmic and antihypertensive activity.
Manufacturing Process
1,7-Bis-(3-ethoxyphenyl)-3-methylaza-7-cyano-nonadecane:
0.06 mole of 1-cyano-1-(3-methoxyphenyl)tridecane (prepared by phase
transfer-catalyzed alkylation of 3-methoxyphenylacetonitrile with 1-
bromododecane) and 0.06 mole of 1-chloro-4-methylaza-6-(3-
methoxyphenyl)hexane [prepared from N-methyl-β-(3-
methoxyphenyl)ethylamine and 1-bromo-3-chloropropane by a method similar
to that described in Arzneim.-Forsch. 28 (II) (1978), 2048] were dissolved in
100 ml of dry toluene in a three-necked flask provided with a stirrer, dropping
funnel, reflux condenser and thermometer. 9.3 g (0.07 mole) of a 30%
strength suspension of sodium amide in toluene were then added dropwise at
from 100° to 110°C, with stirring, and stirring was continued under reflux for
a further 90 minutes.
The resulting reaction solution was poured into 200 ml of ice water, and the
toluene phase was separated off and washed twice with water. The required
amount of hydrochloric acid was added to the toluene solution, the toluene
was distilled off under reduced pressure and the residue, which remained was
recrystallized from acetone to give 1,7-bis-(2-methoxyphenyl)-3-methylaza-7-
cyanononadecane hydrochloride or α-dodecyl-3-methoxy-α-[3-[[2-(3-
methoxyphenyl)ethyl]methylamino]propyl]benzene-acetonitrile (anipamil);
MP: 60°-69.5°C.
Therapeutic Function
Coronary vasodilator, Antihypertensive
anipamil Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9030 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7431 | 58 |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | synchempharma@aliyun.com | China | 6444 | 55 |
| Wuhan Magic Biological Technology Co., Ltd. | 18872289958、027-52304252、3400508168 | 3400508168@qq.com | China | 1910 | 55 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29778 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
