GUANOXAN SULFATE
- CAS No.
- 5714-04-5
- Chemical Name:
- GUANOXAN SULFATE
- Synonyms
- Guanoxan Hemisulfate;Guanoxan sulfate USP/EP/BP;(1,4-Benzodioxan-2-ylmethyl)guanidine sulfate;1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)guanidine;1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)Methyl)guanidine sulfate(2:1)
- CBNumber:
- CB41011285
- Molecular Formula:
- 2C10H13N3O2.H2O4S
- Molecular Weight:
- 512.541
- MDL Number:
- MOL File:
- 5714-04-5.mol
- MSDS File:
- SDS
Melting point | >200°C (dec.) |
---|---|
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
Stability | Hygroscopic |
FDA UNII | N6IT80R85G |
GUANOXAN SULFATE price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | G839500 | GuanoxanHemisulfate | 5714-04-5 | 100mg | $1455 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | NUC0000069 | GUANOXANI SULFAS 95.00% | 5714-04-5 | 50G | $3371.45 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | NUC0000069 | GUANOXANI SULFAS 95.00% | 5714-04-5 | 10G | $1431.05 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB41836 | (1,4-Benzodioxan-2-ylmethyl)guanidine sulfate | 5714-04-5 | 10mg | $60 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB41836 | (1,4-Benzodioxan-2-ylmethyl)guanidine sulfate | 5714-04-5 | 25mg | $100 | 2021-12-16 | Buy |
GUANOXAN SULFATE Chemical Properties,Uses,Production
Originator
Envacar,Pfizer
Uses
Antihypertensive.
Uses
Guanoxan is a sympatholytic drug related to Guanethidine (G815000). Guanoxan is used in the treatment of hypertension.
Manufacturing Process
2 Methods of producing of 2-guanidinemethyl-2,3-dihydro-1,4-benzodioxine:
1. 3.3 parts by weight of 2-aminomethyl-1,4-benzodioxane and 2.78 parts by
weight of S-methylisothiouronium sulfate were dissolved in 20 parts by
volume of water, and the resulting aqueous solution was heated under reflux
for 3 h. At the end of this time, the solvent was removed by means of
evaporation under reduced pressure and the residue so obtained dissolved in
a minimum amount of fresh water and treated with charcoal. Upon filtration,
there was obtained a clear filtrate which, on standing, soon afforded pure
crystals of di(2-guanidinomethyl-1,4-benzodioxane)sulfate, melting point
204°-205°C.
The base 2-guanidinemethyl-2,3-dihydro-1,4-benzodioxine may be obtained
by reaction of di(2-guanidinomethyl-1,4-benzodioxane)sulfate with, for
example, sodium hydroxide.
2. o-Dihydroxybenzene reacted with epichlorhydrine in the presence sodium
hydroxide and 2-hydroxymethyl-2,3-dihydro-1,4-benzodioxine was obtained.
To solution of 2-hydroxymethyl-2,3-dihydro-1,4-benzodioxine thionylchloride
was added to give 2-chlormethyl-2,3-dihydro-1,4-benzodioxine.
2-Chloromethyl-2,3-dihydro-1,4-benzodioxine reacted with benzylamine to
produced 2-benzylaminomethyl-2,3-dihydro-1,4-benzodioxine, which was
reduced at the presence of hydrogen and Pd-C (catalyst) to 2-aminomethyl-
2,3-dihydro-1,4-benzodioxine.
2-Aminomethyl-2,3-dihydro-1,4-benzodioxine was treated by Smethylisothiouronium sulfate and there was produced 2-guanidinemethyl-2,3-
dihydro-1,4-benzodioxine.
brand name
Envacar (Pfizer).
Therapeutic Function
Antihypertensive
GUANOXAN SULFATE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 23430 | 58 |
Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5905 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10991 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Chemwill Asia Co.,Ltd. | 86-21-51086038 | chemwill_asia@126.com | CHINA | 23931 | 58 |
Hangzhou Yuhao Chemical Technology Co., Ltd | 0571-82693216 | info@yuhaochemical.com | China | 9394 | 52 |
Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9900 | 58 | |
Shanghai QianYan Bio-technology Co., Ltd | 02781293128 | orders@biochemsafebuy.com | China | 9934 | 55 |
View Lastest Price from GUANOXAN SULFATE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-08-11 | Guanoxan sulfate USP/EP/BP | US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | ||
2020-05-10 | Guanoxan
5714-04-5
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
- Guanoxan sulfate USP/EP/BP
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
- Guanoxan
5714-04-5
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd