ChemicalBook >> CAS DataBase List >>3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo-

3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo-

3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- structure

CAS No.: 2415225-30-6

Chemical Name:: 3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo-

Synonyms: Acid Ceramidase-IN-1;3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo-

CBNumber:: CB410636529

Molecular Formula:: C18H25N3O3

Molecular Weight:: 331.41

MDL Number:

MOL File:: 2415225-30-6.mol

Last updated:2024-07-02 08:55:07

Request For Quotation

3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Properties

Density	1.186±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
pka	13.11±0.20(Predicted)
form	Solid
color	White to yellow

3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Chemical Properties,Uses,Production

Biological Activity

Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice[1].

References

[1]. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664.

3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4552	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28091	58

Supplier	Advantage
Nantong QuanYi Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58

3(2H)-Benzoxazolecarboxamide, 6-(1-methyl-4-piperidinyl)-N-(2-methylpropyl)-2-oxo- Acid Ceramidase-IN-1 2415225-30-6