ChemicalBook >> CAS DataBase List >>3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-
- CAS No.
- 2413574-64-6
- Chemical Name:
- 3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-
- Synonyms
- FG-944;LpxC-IN-10;LpxC-IN-10 (Compound A);3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-
- CBNumber:
- CB410647529
- Molecular Formula:
- C30H31N5O3
- Molecular Weight:
- 509.6
- MDL Number:
- MOL File:
- 2413574-64-6.mol
Last updated:2024-07-02 08:55:07
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Properties
Boiling point | 717.7±70.0 °C(Predicted) |
---|---|
Density | 1.27±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
form | Solid |
pka | 8?+-.0.50(Predicted) |
color | White to off-white |
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Chemical Properties,Uses,Production
Biological Activity
LpxC-IN-10 (Compound A) is a high selectivity inhibitor of LpxC. LpxC-IN-10 exhibits MIC values of 0.5 μg/mL against E. coli and K. pneumoniae. LpxC-IN-10 (Compound A) can be used for the research of bacterial infection[1]. LpxC-IN-10 (Compound A) shows MIC value < 1 pg/mL to E. coli and K. pneumoniae[1].
References
[1]. Min T, et al. LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF:, US20210315902A1[P]. 2021.
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 994 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
Supplier | Advantage |
---|---|
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 58 |
TargetMol Chemicals Inc. | 58 |
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-
LpxC-IN-10 (Compound A)
LpxC-IN-10
FG-944
2413574-64-6