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ChemicalBook >> CAS DataBase List >>3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-

3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-

3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Structure
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- structure
CAS No.
2413574-64-6
Chemical Name:
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-
Synonyms
FG-944;LpxC-IN-10;LpxC-IN-10 (Compound A);3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-
CBNumber:
CB410647529
Molecular Formula:
C30H31N5O3
Molecular Weight:
509.6
MDL Number:
MOL File:
2413574-64-6.mol
Last updated:2024-07-02 08:55:07
Request For Quotation

3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Properties

Boiling point 717.7±70.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 8?+-.0.50(Predicted)
color White to off-white

3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Chemical Properties,Uses,Production

Biological Activity

LpxC-IN-10 (Compound A) is a high selectivity inhibitor of LpxC. LpxC-IN-10 exhibits MIC values of 0.5 μg/mL against E. coli and K. pneumoniae. LpxC-IN-10 (Compound A) can be used for the research of bacterial infection[1]. LpxC-IN-10 (Compound A) shows MIC value < 1 pg/mL to E. coli and K. pneumoniae[1].

References

[1]. Min T, et al. LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF:, US20210315902A1[P]. 2021.

3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 994 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23963 58
Supplier Advantage
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- LpxC-IN-10 (Compound A) LpxC-IN-10 FG-944 2413574-64-6