6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE

CAS No.
1140-81-4
Chemical Name:
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
Synonyms
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE;6-Acetamido-2-methyl-4-hydroxyquinoline;N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine;N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide;N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide;N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide;Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)-;n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
CBNumber:
CB41091481
Molecular Formula:
C12H12N2O2
Molecular Weight:
216.24
MDL Number:
MOL File:
1140-81-4.mol
MSDS File:
SDS
Last updated:2024-08-05 20:55:42

6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Properties

Melting point >300 °C
Boiling point 496.0±40.0 °C(Predicted)
Density 1.314±0.06 g/cm3(Predicted)
solubility Ethyl Acetate; Toluene
pka 4.29±0.40(Predicted)
form Solid
color Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P

6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T323233 N-(4-HYDROXY-2-METHYL-6-QUINOLINYL)ACETAMIDE AldrichCPR 1140-81-4 5MG $70.9 2024-03-01 Buy
TRC H114085 N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide 1140-81-4 1g $430 2021-12-16 Buy
AK Scientific 9559AJ 6-Acetamido-4-hydroxy-2-methylquinoline 1140-81-4 250mg $552 2021-12-16 Buy
Biosynth Carbosynth FA152500 6-Acetamido-2-methyl-4-hydroxyquinoline 1140-81-4 500mg $645 2021-12-16 Buy
Biosynth Carbosynth FA152500 6-Acetamido-2-methyl-4-hydroxyquinoline 1140-81-4 50mg $107 2021-12-16 Buy
Product number Packaging Price Buy
T323233 5MG $70.9 Buy
H114085 1g $430 Buy
9559AJ 250mg $552 Buy
FA152500 500mg $645 Buy
FA152500 50mg $107 Buy

6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Chemical Properties,Uses,Production

Uses

N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 4065, 1948 DOI: 10.1021/ja01192a031

244219-89-4
1140-81-4
Synthesis of 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE from (E)-Methyl 3-(4-acetaMidophenyliMino)butanoate

6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE Preparation Products And Raw materials

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630 bess@weibangbio.com China 18153 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Shanghai JiYi Biotechnology Co. Ltd. 13621943973 sales@shjiyipharmatech.com China 1166 55
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 5902 65
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3251 58
Carbosynth -- sales@carbosynth.com United Kingdom 6005 58

View Lastest Price from 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE pictures 2024-08-05 6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE
1140-81-4
US $0.00-0.00 / KG 1KG 99.0% 10 tons Shaanxi Dideu Medichem Co. Ltd
6-ACETAMIDO-4-HYDROXY-2-METHYLQUINOLINE N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine N-(4-hydroxy-2-Methylquinolin-6-yl)acetaMide N-(2-methyl-4-oxo-1H-quinolin-6-yl)acetamide 6-Acetamido-2-methyl-4-hydroxyquinoline Acetamide, N-(4-hydroxy-2-methyl-6-quinolinyl)- n-(2-Methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide 1140-81-4