ASPERPHENAMATE
- CAS No.
- 63631-36-7
- Chemical Name:
- ASPERPHENAMATE
- Synonyms
- Auranamide;ASPERPHENAMATE;N-Benzoyl-L-phenylalanine (S)-2-benzoylamino-3-phenylpropyl ester;(2S)-2-(Benzoylamino)-3-phenylpropanoic acid (2S)-2-(benzoylamino)-3-phenylpropyl ester
- CBNumber:
- CB41245088
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD30180097
- MOL File:
- 63631-36-7.mol
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble |
| form | A solid |
| color | White to off-white |
| FDA UNII | 2H4MD59YVT |
ASPERPHENAMATE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25086 | Asperphenamate ≥95% | 63631-36-7 | 1mg | $305 | 2024-03-01 | Buy |
| Cayman Chemical | 25086 | Asperphenamate ≥95% | 63631-36-7 | 5mg | $1139 | 2024-03-01 | Buy |
| ChemScene | CS-0106762 | Asperphenamate ≥98.0% | 63631-36-7 | 5mg | $580 | 2021-12-16 | Buy |
| ChemScene | CS-0106762 | Asperphenamate ≥98.0% | 63631-36-7 | 10mg | $800 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0171-C250 | Asperphenamate ≥95%(HPLC) | 63631-36-7 | 250μg | $90 | 2021-12-16 | Buy |
ASPERPHENAMATE Chemical Properties,Uses,Production
Description
Asperphenamate is a fungal secondary metabolite originally isolated from A. flavipes. It inhibits proliferation of T47D and MDA-MB-231 breast and HL-60 leukemia cancer cell lines (IC50s = 92.3, 96.5, and 97.9 μM, respectively) and inhibits yeast α-glucosidase activity (IC50 = 8.3 μM).
Uses
Asperphenamate is an α-glucosidase inhibitor isolated from Penicillium spathulatum. Asperphenamate exhibits anticancer properties and is used to synthesize N-Benzoyl-O-(N''-(1-benzyloxycarbonyl-4-piperidiylcarbonyl)-D-phenylalanyl)-D-phenylalaninol (BBP), an asperphenamate derivative that inhibits human breast carcinoma MCF-7 cell growth.
Definition
ChEBI: Asperphenamate is a carboxylic ester resulting from the formal condensation of the carboxy group of N-benzoyl-L-phenylalanine with the hydroxy group of N-benzoyl-L-phenylalaninol. A metabolite found in several Pencillium and Aspergillus species, as well as in plants as a product of endophytic fungi. It has a role as an antineoplastic agent. It is a L-phenylalanine derivative, a member of benzamides and a carboxylic ester. It is functionally related to a N-benzoyl-L-phenylalanine and a N-benzoyl-L-phenylalaninol.
ASPERPHENAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
ASPERPHENAMATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8864 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |