ANTI-HUMAN FACTOR V
- CAS No.
- Chemical Name:
- ANTI-HUMAN FACTOR V
- Synonyms
- ANTI-HUMAN FACTOR V;ANTI-FACTOR V, HUMAN;ANTI-FACTOR V (HEAVY CHAIN);ANTI-FACTOR V (LIGHT CHAIN);ANTI-HUMAN FACTOR V, LIGHT CHAIN;Monoclonal Anti-Factor V antibody produced in mouse
- CBNumber:
- CB4128807
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00164642
- MOL File:
- Mol file
ANTI-HUMAN FACTOR V price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F2145 | Monoclonal Anti-Factor V antibody produced in mouse clone HV-1, purified immunoglobulin, buffered aqueous solution | 100μL | $485 | 2024-03-01 | Buy | |
| American Custom Chemicals Corporation | ATB0010930 | ANTI-HUMAN FACTOR V 95.00% | 5MG | $503.38 | 2021-12-16 | Buy |
ANTI-HUMAN FACTOR V Chemical Properties,Uses,Production
Uses
Monoclonal Anti-Factor V antibody produced in mouse has been used in dot blot and enzyme linked immunosorbent assay (ELISA).
General Description
Monoclonal Anti-Factor V (mouse IgG1 isotype) is derived from the HV-1 hybridoma, produced by the fusion of mouse myeloma Sp2/0-Ag14 cells and splenocytes from BALB/c mouse immunized with Factor V, purified from human plasma. Blood coagulation factor V, also known as, proaccelerin or labile factor. The activated factor V (factor Va) is a calcium dependent heterodimer composed of heavy chain (~105 kDa) and light chain (~73 kDa).
Biochem/physiol Actions
Blood coagulation factor V is an essential component of the prothrombinase complex that catalyzes the rapid conversion of prothrombin to thrombin and is involved in intrinsic and extrinsic coagulation pathways. About 20% of blood factor V is contained within platelets. Factor V circulates in the plasma as a single chain glycoprotein with little or no intrinsic procoagulant activity. It is activated through limited proteolysis by thrombin, factor Xa, or the factor V activator from Russell′s viper venom (RW-V). Activated protein C (APC) with its cofactor protein S, inactivates factors Va and VIIIa to provide a major natural anticoagulant system. APC resistance known as factor V Leiden (FV Leiden) is a common hereditary thrombophilia Factor V mutation, caused by arginine substitution into glutamine at position 506 (R506Q).
ANTI-HUMAN FACTOR V Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN FACTOR V Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| SIGMA-RBI | -- | Switzerland | 6913 | 91 | |
| Kanto Chemical Co., Inc. | -- | reag-info@gms.kanto.co.jp | Japan | 6762 | 74 |
| American Diagnostica Inc. | -- | services@amdiag.com | United States | 225 | 59 |
| Chemicon Internatinal, Inc. | -- | custserv@chemicon.com | United States | 4175 | 65 |
| BIODESIGN International/OEM Concepts | -- | info@biodesign.com | United States | 2376 | 50 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| SIGMA-RBI | 91 |
| Kanto Chemical Co., Inc. | 74 |
| American Diagnostica Inc. | 59 |
| Chemicon Internatinal, Inc. | 65 |
| BIODESIGN International/OEM Concepts | 50 |