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licarin B

CAS No.
51020-87-2
Chemical Name:
licarin B
Synonyms
licarin B;Licarine B;(-)-Licarin B;5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole;5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole;5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole;1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-;1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI);5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
CBNumber:
CB41314632
Molecular Formula:
C20H20O4
Molecular Weight:
324.37
MDL Number:
MFCD13195533
MOL File:
51020-87-2.mol
Last updated:2024-11-19 23:02:33

licarin B Properties

Boiling point 428.5±45.0 °C(Predicted)
Density 1.201±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder
color White

licarin B price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology N1572 (-)-LicarinB 51020-87-2 20mg $250 2021-12-16 Buy
AK Scientific Y1205 licarinB 51020-87-2 25mg $336 2021-12-16 Buy
Crysdot CD11113736 LicarinB 97% 51020-87-2 50mg $353 2021-12-16 Buy
Chemenu CM161067 5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole 97% 51020-87-2 100mg $468 2021-12-16 Buy
Crysdot CD11113736 LicarinB 97% 51020-87-2 100mg $641 2021-12-16 Buy
Product number Packaging Price Buy
N1572 20mg $250 Buy
Y1205 25mg $336 Buy
CD11113736 50mg $353 Buy
CM161067 100mg $468 Buy
CD11113736 100mg $641 Buy

licarin B Chemical Properties,Uses,Production

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from nutmeg, Lauraceae (Lauraceae) Licarin aritu Ducke trunk (yield: 0.35%) Machilus japonica Sieb.et Zucc. Ye Hongnan Machilus thunbergii Sieb.et Zucc. Bark, wood, leaves.

Uses

Licarin B has antibacterial, anti-inflammatory, sedative and anti-tumor effects.

Biological Activity

Licarin B, derived from the seeds of Myristica fragrans, is an inhibitor of NO production and improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway.

in vitro

Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes.

Cell Viability Assay < /p>

Cell Line: 3T3-L1 cell.
Concentration: 1-500 μM.
Incubation Time: 48 h.
Result: Did not cause significant cell death up to 500 μM concentration.

Cell Viability Assay

td>
Cell Line: 3T3-L1 cell.
Concentration: 5 μM, 10 μM, 15 μM.
Incubation Time: 8 days (replaced every 2 days). 8 days (replaced every 2 days).
Result: LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation.
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target

PPAR | GLUT | PI3K | Akt | IRS-1

licarin B Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 135)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29882 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2993 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58

View Lastest Price from licarin B manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Licarin B pictures 2024-11-19 Licarin B
51020-87-2
US $33.00-110.00 / mg ≥95% 10g TargetMol Chemicals Inc.
(-)-Licarin B pictures 2023-02-24 (-)-Licarin B
51020-87-2
US $0.00 / mg 20mg ≥98%(HPLC) 100 g Shanghai Standard Technology Co., Ltd.
licarin B pictures 2019-07-06 licarin B
51020-87-2
US $1.00 / kg 1 mg 99% 100KG Career Henan Chemical Co
  • Licarin B pictures
  • Licarin B
    51020-87-2
  • US $33.00-110.00 / mg
  • ≥95%
  • TargetMol Chemicals Inc.
  • (-)-Licarin B pictures
  • (-)-Licarin B
    51020-87-2
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • licarin B pictures
  • licarin B
    51020-87-2
  • US $1.00 / kg
  • 99%
  • Career Henan Chemical Co
1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI) licarin B 5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole 5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole 5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole Licarine B 1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]- (-)-Licarin B 5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole 51020-87-2 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract reagent standard substance