licarin B
- CAS No.
- 51020-87-2
- Chemical Name:
- licarin B
- Synonyms
- licarin B;Licarine B;(-)-Licarin B;5-[(2S)-2,3-Dihydro-7-methoxy-3β-methyl-5-[(E)-1-propenyl]benzofuran-2-yl]-1,3-benzodioxole;5-((2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl)-1,3-benzodioxole;5-[(3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]-1,3-benzodioxole;1,3-Benzodioxole, 5-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-;1,3-Benzodioxole,5-[(2R,3R)-2,3-dihydro-7-Methoxy-3-Methyl-5-(1E)-1-propenyl-2-benzofuranyl]-(9CI);5-((2R,3R)-7-Methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole
- CBNumber:
- CB41314632
- Molecular Formula:
- C20H20O4
- Molecular Weight:
- 324.37
- MDL Number:
- MFCD13195533
- MOL File:
- 51020-87-2.mol
licarin B price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ApexBio Technology | N1572 | (-)-LicarinB | 51020-87-2 | 20mg | $250 | 2021-12-16 | Buy |
AK Scientific | Y1205 | licarinB | 51020-87-2 | 25mg | $336 | 2021-12-16 | Buy |
Crysdot | CD11113736 | LicarinB 97% | 51020-87-2 | 50mg | $353 | 2021-12-16 | Buy |
Chemenu | CM161067 | 5-((2R,3R)-7-methoxy-3-methyl-5-((E)-prop-1-en-1-yl)-2,3-dihydrobenzofuran-2-yl)benzo[d][1,3]dioxole 97% | 51020-87-2 | 100mg | $468 | 2021-12-16 | Buy |
Crysdot | CD11113736 | LicarinB 97% | 51020-87-2 | 100mg | $641 | 2021-12-16 | Buy |
licarin B Chemical Properties,Uses,Production
Chemical Properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from nutmeg, Lauraceae (Lauraceae) Licarin aritu Ducke trunk (yield: 0.35%) Machilus japonica Sieb.et Zucc. Ye Hongnan Machilus thunbergii Sieb.et Zucc. Bark, wood, leaves.
Uses
Licarin B has antibacterial, anti-inflammatory, sedative and anti-tumor effects.
Biological Activity
Licarin B, derived from the seeds of Myristica fragrans, is an inhibitor of NO production and improves insulin sensitivity by activating PPARγ and GLUT4 in the IRS-1/PI3K/AKT pathway.
in vitro
Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes.
Cell Viability Assay < /p>
Cell Line: | 3T3-L1 cell. |
Concentration: | 1-500 μM. |
Incubation Time: | 48 h. |
Result: | Did not cause significant cell death up to 500 μM concentration. |
Cell Viability Assay
Cell Line: | 3T3-L1 cell. | |
Concentration: | 5 μM, 10 μM, 15 μM. | |
Incubation Time: | 8 days (replaced every 2 days). | 8 days (replaced every 2 days). | td>
Result: | LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation. |
target
PPAR | GLUT | PI3K | Akt | IRS-1
licarin B Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2993 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
View Lastest Price from licarin B manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | Licarin B
51020-87-2
|
US $33.00-110.00 / mg | ≥95% | 10g | TargetMol Chemicals Inc. | |||
2023-02-24 | (-)-Licarin B
51020-87-2
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 100 g | Shanghai Standard Technology Co., Ltd. | ||
2019-07-06 | licarin B
51020-87-2
|
US $1.00 / kg | 1 mg | 99% | 100KG | Career Henan Chemical Co |
- Licarin B
51020-87-2
- US $33.00-110.00 / mg
- ≥95%
- TargetMol Chemicals Inc.
- (-)-Licarin B
51020-87-2
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
- licarin B
51020-87-2
- US $1.00 / kg
- 99%
- Career Henan Chemical Co