Etimizol
- CAS No.
- 64-99-3
- Chemical Name:
- Etimizol
- Synonyms
- Etimizol;Etimizole;Ethymizol;Antiffine;Ethymisol;Ethimizole;Ethymisole;Etimizol, 99.5%;Ethylnorantifein;Ethylnorantifeine
- CBNumber:
- CB41343533
- Molecular Formula:
- C9H14N4O2
- Molecular Weight:
- 210.23
- MDL Number:
- MFCD00458382
- MOL File:
- 64-99-3.mol
| Melting point | 143-144℃ |
|---|---|
| Boiling point | 563.4±35.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Ethanol: ≥ 33.33 mg/mL (158.54 mM) |
| form | Solid |
| pka | 14.22±0.46(Predicted) |
| color | White to off-white |
| FDA UNII | NG2MF3646P |
Etimizol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FE65019 | Etimizol | 64-99-3 | 50mg | $70 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE65019 | Etimizol | 64-99-3 | 100mg | $125 | 2021-12-16 | Buy |
| AK Scientific | 3660AH | Etimizol | 64-99-3 | 50mg | $144 | 2021-12-16 | Buy |
| AK Scientific | 3660AH | Etimizol | 64-99-3 | 100mg | $218 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE65019 | Etimizol | 64-99-3 | 250mg | $237.5 | 2021-12-16 | Buy |
Etimizol Chemical Properties,Uses,Production
Uses
Etimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). Etimizol can decrease the K-+ permeability of neurons' membrane during action potential.
in vivo
The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement [1]. After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively [2]. Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude [3].
References
[1] Borisova GIu. Effect of etimizol on instrumental learning in rats. Biull Eksp Biol Med. 1985 Jun;99(6):705-6. PMID:4016262
[2] Trnovec T, et al. Etimizol absorption from the small intestine in dogs: the dependence on dosage. Biull Eksp Biol Med. 1986 Dec;102(12):729-30. PMID:3801627
[3] Vislobokov AI, et al. Elektrophysiological parameters of mollusk neurons under the influence of etimizol. Fiziol Zh SSSR Im I M Sechenova. 1975 Jun;61(6):917-24. PMID:1132537
Etimizol Preparation Products And Raw materials
Raw materials
Preparation Products
Etimizol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2782 | 58 |
| AdooQ Bioscience CHINA | 025-58849295 18951903616; | info@adooq.cn | China | 2990 | 60 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17687 | 55 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3866 | 58 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14603 | 60 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4660 | 60 |
