GW0742
- CAS No.
- 317318-84-6
- Chemical Name:
- GW0742
- Synonyms
- GW0742;CS-2560;GW 0742X;GW 610742;GWdelta 0742;Sarms Gw0742;GW0742 sarms;GW0742 / GW0742;GW0742(GW610742);GW0742 USP/EP/BP
- CBNumber:
- CB4138491
- Molecular Formula:
- C21H17F4NO3S2
- Molecular Weight:
- 471.49
- MDL Number:
- MFCD07369423
- MOL File:
- 317318-84-6.mol
- MSDS File:
- SDS
Melting point | 134.5-135.5 °C |
---|---|
Boiling point | 591.5±60.0 °C(Predicted) |
Density | 1.46±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: >5 mg/mL |
form | solid |
pka | 3.17±0.10(Predicted) |
color | white |
InChI | InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28) |
InChIKey | HWVNEWGKWRGSRK-UHFFFAOYSA-N |
SMILES | C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C(F)=C3)=NC=2C)C=C1C |
FDA UNII | 4PZK9FJC4Z |
GW0742 price More Price(32)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | G3295 | GW0742 ≥98% (HPLC) | 317318-84-6 | 1mg | $233 | 2024-03-01 | Buy |
Sigma-Aldrich | G3295 | GW0742 ≥98% (HPLC) | 317318-84-6 | 5mg | $798 | 2024-03-01 | Buy |
Cayman Chemical | 10006798 | GW 0742 ≥95% | 317318-84-6 | 5mg | $81 | 2024-03-01 | Buy |
Cayman Chemical | 10006798 | GW 0742 ≥95% | 317318-84-6 | 10mg | $152 | 2024-03-01 | Buy |
Cayman Chemical | 10006798 | GW 0742 ≥95% | 317318-84-6 | 25mg | $356 | 2024-03-01 | Buy |
GW0742 Chemical Properties,Uses,Production
Description
GW0742 is a PPARδ/β agonist very similar in molecular structure to GW501516 (Cardarine) — with the exception of one atom. It is often mentioned in comparison with Cardarine. This drug is mostly used by athletes to improve their stamina. The fat affecting properties of GW0742 also make it a good promoter of energy in the body. Additionally, this drug helps increase the oxidative abilities of your body muscles.
Chemical Properties
Light Yellow Solid
Uses
GW0742 is a small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.
Definition
ChEBI: GW 0742 is a monocarboxylic acid.
Biological Activity
GW 0742 is a potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.
storage
Desiccate at +4°C
GW0742 Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 902 | 58 |
Wuhan Cell Pharmaceutical Co., Ltd | +86-13129979210 +86-13129979210 | sales@cellwh.com | China | 376 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | Ethan@dornechem.com | China | 3102 | 58 |
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 427 | 58 |
Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 +86-13176845580 | da@zhongda-biotech.com | China | 232 | 58 |
Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 | linda@zhongda-biotech.com | China | 193 | 58 |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1085 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
Shijiazhuang Saixin Technology Co., Ltd. | +86-16632312509 +86-16632315022 | saixinkeji@aliyun.com | China | 86 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
View Lastest Price from GW0742 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-15 | GW0742
317318-84-6
|
US $1.00 / g | 1g | 99% | 100kg | Dorne Chemical Technology co. LTD | ||
2024-11-14 | GW0742
317318-84-6
|
US $43.00-127.00 / mg | 99.85% | 10g | TargetMol Chemicals Inc. | |||
2024-11-14 | GW0742
317318-84-6
|
US $50.00-400.00 / g | 10g | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd |