rugulovasine A

CAS No.
26909-33-1
Chemical Name:
rugulovasine A
Synonyms
RUGULOVASINA;rugulovasine A;Spiro[benz[cd]indole-5(1H),2'(5'H)-furan]-5'-one, 3,4-dihydro-4'-methyl-4-(methylamino)-, (2'R,4S)-rel-
CBNumber:
CB41393543
Molecular Formula:
C16H16N2O2
Molecular Weight:
268.31
MDL Number:
MOL File:
26909-33-1.mol
Last updated:2022-12-21 16:56:50

rugulovasine A Properties

Melting point 138° (dec)
alpha 22436 -3.0° (pyridine)
FDA UNII 90DEE096C5

rugulovasine A Chemical Properties,Uses,Production

Description

A non-crystallizable alkaloid, this base has been obtained from cultures of Penicillium concavorugulosum. It is slightly laevorotatory with [α]22436 - 3.0° (c 1.0, pyridine). The five-membered lactone ring is unsaturated and on catalytic hydrogenation the alkaloid forms the crystalline dihydro derivative, m.p. l49-l5l oC. One of the nitrogen atoms is present in the indole ring, the other being a methylamino group.

References

Abe et al., Agr. Bioi. Chern., (Tokyo), 33, 469 (1969)
Abe et al., Nippon Nogeikagaku Kaishi, 43, 575 (1969)
Yamatodani et al., Agr. Bioi. Chern., (Tokyo), 34,485 (1970)

rugulovasine A Preparation Products And Raw materials

Raw materials

Preparation Products

rugulovasine A RUGULOVASINA Spiro[benz[cd]indole-5(1H),2'(5'H)-furan]-5'-one, 3,4-dihydro-4'-methyl-4-(methylamino)-, (2'R,4S)-rel- 26909-33-1