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FRAXINOL

FRAXINOL structure

CAS No.: 486-28-2

Chemical Name:: FRAXINOL

Synonyms: Fraxil;FRAXINOL;Fraxinol-RM;Fraxinol, 10 mM in DMSO;5,7-Dimethoxy-6-hydroxycoumarin;6-Hydroxy-5,7-dimethoxycoumarin;6-Hydroxy-5,7-dimethoxy-chromen-2-one;6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one;6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy-

CBNumber:: CB41437012

Molecular Formula:: C11H10O5

Molecular Weight:: 222.19

MDL Number:: MFCD08693526

MOL File:: 486-28-2.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:16

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FRAXINOL Properties

Melting point	170-172℃
Boiling point	449.7±45.0 °C(Predicted)
Density	1.358
storage temp.	Store at -20°C
solubility	Soluble in DMSO and methanol;
pka	8.95±0.20(Predicted)
form	powder
color	White-yellowish
Water Solubility	slightly soluble in water
CAS DataBase Reference	486-28-2
FDA UNII	U330651DTI
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P330-P501

NFPA 704

	0
2		0

FRAXINOL price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	28218	Fraxinol	486-28-2	1mg	$49	2024-03-01	Buy
Cayman Chemical	28218	Fraxinol	486-28-2	10mg	$310	2024-03-01	Buy
Cayman Chemical	28218	Fraxinol	486-28-2	5mg	$179	2024-03-01	Buy
Usbiological	361791	Fraxinol	486-28-2	20mg	$581	2021-12-16	Buy
Biorbyt Ltd	orb594389	Fraxinol	486-28-2	20mg	$591.6	2021-12-16	Buy

Product number	Packaging	Price	Buy
28218	1mg	$49	Buy
28218	10mg	$310	Buy
28218	5mg	$179	Buy
361791	20mg	$581	Buy
orb594389	20mg	$591.6	Buy

FRAXINOL Chemical Properties,Uses,Production

Description

Fraxinol is a coumarin originally isolated from Ash tree bark. It inhibits growth of GLC-4 small cell lung carcinoma and COLO 320 colorectal cancer cells (IC₅₀s = 193 and 165 μM, respectively). Fraxinol potentiates barbiturate-induced sleep in rats and rabbits.

Uses

Fraxinol is isolated from Lobelia chinensis[1].

References

[1] Wei J, et al. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharm Biol. 2018 Dec;56(1):363-367. DOI:10.1080/13880209.2018.1491999

FRAXINOL Preparation Products And Raw materials

Raw materials

Preparation Products

FRAXINOL Suppliers

Global( 119)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3772	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29808	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569262 +86-15003564040	1087@dideu.com	China	3270	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Apeloa Pharmaceutical Co., Ltd.	+86-0571-87635730 +8615858229168	chem1022@hengdian-group.com	China	1478	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei xin bonus chemical co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Wuhan ChemNorm Biotech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Apeloa Pharmaceutical Co., Ltd.	58

View Lastest Price from FRAXINOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-01-03	Fraxinol 486-28-2	US $0.00-0.00 / KG	5mg	99%HPLC	2000tons	Shaanxi Dideu Medichem Co. Ltd
2024-11-19	Fraxinol 486-28-2	US $132.00 / mg		≥95%	10g	TargetMol Chemicals Inc.
2020-01-10	6-hydroxy-5,7-dimethoxychromen-2-one 486-28-2	US $9.80 / KG	1KG	≥98%	20 tons	Career Henan Chemical Co

Fraxinol
486-28-2
US $0.00-0.00 / KG
99%HPLC
Shaanxi Dideu Medichem Co. Ltd

Fraxinol
486-28-2
US $132.00 / mg
≥95%
TargetMol Chemicals Inc.

6-hydroxy-5,7-dimethoxychromen-2-one
486-28-2
US $9.80 / KG
≥98%
Career Henan Chemical Co

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1of3

FRAXINOL 5,7-Dimethoxy-6-hydroxycoumarin 6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one 6-Hydroxy-5,7-dimethoxycoumarin Fraxil 6-Hydroxy-5,7-dimethoxy-chromen-2-one 6-Hydroxy-5,7-dimethoxy-2H-chromen-2-one 2H-1-Benzopyran-2-one, 6-hydroxy-5,7-dimethoxy- Fraxinol-RM Fraxinol, 10 mM in DMSO 486-28-2