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SPIROXATRINE

CAS No.
1054-88-2
Chemical Name:
SPIROXATRINE
Synonyms
R 5188;SPIROXATRINE;Spiroxatrine (R 5188);SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5;8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-;8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE;R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one
CBNumber:
CB4157162
Molecular Formula:
C22H25N3O3
Molecular Weight:
379.45
MDL Number:
MFCD00055134
MOL File:
1054-88-2.mol
Last updated:2024-11-17 16:00:36

SPIROXATRINE Properties

Melting point 215.8-218.0 °C
Boiling point 602.8±55.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility 0.1 M HCl: moderately soluble
pka 15.03±0.20(Predicted)
form powder
color white
FDA UNII DR0QR50ALL

SAFETY

Risk and Safety Statements

WGK Germany  3

SPIROXATRINE price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 0631 Spiroxatrine 1054-88-2 10 $145 2021-12-16 Buy
Tocris 0631 Spiroxatrine 1054-88-2 50 $593 2021-12-16 Buy
TRC S683503 Spiroxatrine(R5188) 1054-88-2 10mg $105 2021-12-16 Buy
Usbiological 466452 Spiroxatrine 1054-88-2 10mg $382 2021-12-16 Buy
Usbiological 256729 Spiroxatrine 1054-88-2 10mg $389 2021-12-16 Buy
Product number Packaging Price Buy
0631 10 $145 Buy
0631 50 $593 Buy
S683503 10mg $105 Buy
466452 10mg $382 Buy
256729 10mg $389 Buy

SPIROXATRINE Chemical Properties,Uses,Production

Uses

Spiroxatrine (R 5188) is a SR-1A antagonist.

Definition

ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines.

Biological Activity

5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.

SPIROXATRINE Preparation Products And Raw materials

Raw materials

Preparation Products

SPIROXATRINE Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
BOC Sciences -- info@bocsci.com USA 0 65
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44808 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8617 58

View Lastest Price from SPIROXATRINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Spiroxatrine pictures 2024-11-17 Spiroxatrine
1054-88-2
US $80.00-263.00 / mg 99.83% 10g TargetMol Chemicals Inc.
SPIROXATRINE pictures 2024-07-07 SPIROXATRINE
1054-88-2
US $0.10 / KG 1KG 98.0% 10 Shaanxi Dideu Medichem Co. Ltd
  • Spiroxatrine pictures
  • Spiroxatrine
    1054-88-2
  • US $80.00-263.00 / mg
  • 99.83%
  • TargetMol Chemicals Inc.
  • SPIROXATRINE pictures
  • SPIROXATRINE
    1054-88-2
  • US $0.10 / KG
  • 98.0%
  • Shaanxi Dideu Medichem Co. Ltd
SPIROXATRINE R 5188 (+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE 8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5 R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one Spiroxatrine (R 5188) 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl- 8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 1054-88-2 Serotonin receptor