ChemicalBook >> CAS DataBase List >>SPIROXATRINE
SPIROXATRINE
- CAS No.
- 1054-88-2
- Chemical Name:
- SPIROXATRINE
- Synonyms
- R 5188;SPIROXATRINE;Spiroxatrine (R 5188);SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5;8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-;8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE;R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one
- CBNumber:
- CB4157162
- Molecular Formula:
- C22H25N3O3
- Molecular Weight:
- 379.45
- MDL Number:
- MFCD00055134
- MOL File:
- 1054-88-2.mol
Last updated:2024-07-07 20:48:41
Melting point | 215.8-218.0 °C |
---|---|
Boiling point | 602.8±55.0 °C(Predicted) |
Density | 1.32±0.1 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | 0.1 M HCl: moderately soluble |
pka | 15.03±0.20(Predicted) |
form | powder |
color | white |
FDA UNII | DR0QR50ALL |
SPIROXATRINE price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 0631 | Spiroxatrine | 1054-88-2 | 10 | $145 | 2021-12-16 | Buy |
Tocris | 0631 | Spiroxatrine | 1054-88-2 | 50 | $593 | 2021-12-16 | Buy |
TRC | S683503 | Spiroxatrine(R5188) | 1054-88-2 | 10mg | $105 | 2021-12-16 | Buy |
Usbiological | 466452 | Spiroxatrine | 1054-88-2 | 10mg | $382 | 2021-12-16 | Buy |
Usbiological | 256729 | Spiroxatrine | 1054-88-2 | 10mg | $389 | 2021-12-16 | Buy |
SPIROXATRINE Chemical Properties,Uses,Production
Uses
Spiroxatrine (R 5188) is a SR-1A antagonist.
Definition
ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines.
Biological Activity
5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.
SPIROXATRINE Preparation Products And Raw materials
Raw materials
Preparation Products
SPIROXATRINE Suppliers
Global( 42)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3415 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
View Lastest Price from SPIROXATRINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-07-07 | SPIROXATRINE
1054-88-2
|
US $0.10 / KG | 1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd |
-
- SPIROXATRINE
1054-88-2
- US $0.10 / KG
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
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SPIROXATRINE
R 5188
(+/-)-8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZA-SPIRO[4,5]DECAN-4-ONE
8-[(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE
SPIROXATRINE (R 5188) SELECTIVE SEROTONI N 5
R 5188, (±)-8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one
Spiroxatrine (R 5188)
8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-
8-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
1054-88-2
Serotonin receptor