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2-(3-Chloro-phenyl)-pyrrolidine

2-(3-Chloro-phenyl)-pyrrolidine structure

CAS No.: 298690-74-1

Chemical Name:: 2-(3-Chloro-phenyl)-pyrrolidine

Synonyms: AKOS BB-8867;CHEMBRDG-BB 4006410;2-(3-CHLOROPHENYL)PYRROLIDINE;Pyrrolidine, 2-(3-chlorophenyl)-;(+/-)-2-(3-chlorophenyl)-pyrrolidine

CBNumber:: CB4175836

Molecular Formula:: C10H12ClN

Molecular Weight:: 181.66

MDL Number:: MFCD02663429

MOL File:: 298690-74-1.mol

Last updated:2023-10-11 11:15:29

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2-(3-Chloro-phenyl)-pyrrolidine Properties

Boiling point	138-141 °C(Press: 16 Torr)
Density	1.129±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
pka	9.58±0.10(Predicted)
CAS DataBase Reference	298690-74-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05,GHS07,GHS08,GHS09
Signal word	Danger
Hazard statements	H302-H314-H361-H410
Precautionary statements	P501-P273-P270-P202-P201-P264-P280-P391-P308+P313-P303+P361+P353-P301+P330+P331-P363-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P405
Hazard Codes	Xi
Risk Statements	36
Safety Statements	26
HS Code	2933998090

2-(3-Chloro-phenyl)-pyrrolidine price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C350775	2-(3-Chlorophenyl)pyrrolidine	298690-74-1	100mg	$45	2021-12-16	Buy
Apolloscientific	OR962418	2-(3-Chlorophenyl)pyrrolidine 97%	298690-74-1	5g	$345	2021-12-16	Buy
Apolloscientific	OR962418	2-(3-Chlorophenyl)pyrrolidine 97%	298690-74-1	1g	$115	2021-12-16	Buy
AK Scientific	3067AB	2-(3-Chlorophenyl)pyrrolidine	298690-74-1	1g	$246	2021-12-16	Buy
Biosynth Carbosynth	FC50791	2-(3-Chlorophenyl)pyrrolidine	298690-74-1	1g	$260.6	2021-12-16	Buy

Product number	Packaging	Price	Buy
C350775	100mg	$45	Buy
OR962418	5g	$345	Buy
OR962418	1g	$115	Buy
3067AB	1g	$246	Buy
FC50791	1g	$260.6	Buy

2-(3-Chloro-phenyl)-pyrrolidine Chemical Properties,Uses,Production

Uses

Used as an intermediate for organic synthesis.

Application

(+/-)-2-(3-chlorophenyl)-pyrrolidine has a wide application in synthesis of pharma intermediates，It is also used as an antioxidant.

Reactions

2-(3-Chloro-phenyl)-pyrrolidine is an important building block for the synthesis of various organic compounds. Through the coupling of the amine, It could be employed to couple with 4-(4-formylphenoxy)-1-naphthamide to synthesize 4-[4-[2-(3-Chlorophenyl)pyrrolidin-1-yl]methylphenoxyl]-1-naphthamide which is an aminobenzyloxyarylamide derivatives and act as κ opioid receptor antagonists.

Synthesis

To a solution of substituted benzoic acid inabsolute ethyl alcohol was slowly added thionyl chloride. The mixture was heated to reflux for 2h, and then cooledto room temperature. The solvent was removed and the solid residuewas dissolved in ethyl acetate, and washed withsaturated NaHCO₃ solution. After a series of reactions, 3-(2-chloro-phenyl)-pyrrolidine can be obtained.

2-(3-Chloro-phenyl)-pyrrolidine synthesis

Synthesis of 2-(3-Chloro-phenyl)-pyrrolidine from 3-Chlorobenzoic acid

2-(3-Chloro-phenyl)-pyrrolidine Preparation Products And Raw materials

Raw materials

3-Chlorobenzoic acid

Preparation Products

2-(3-Chloro-phenyl)-pyrrolidine Suppliers

Global( 75)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Tianjin Xinghan Biotechnology Co., Ltd	+8618698089028	1725517238@qq.com	China	2479	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29812	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49979	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32343	55

Supplier	Advantage
Tianjin Xinghan Biotechnology Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
GIHI CHEMICALS CO.,LIMITED	58
Amadis Chemical Company Limited	58
Mainchem Co., Ltd.	55

View Lastest Price from 2-(3-Chloro-phenyl)-pyrrolidine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-24	3-(2-CHLORO-PHENYL)-PYRROLIDINE 298690-74-1	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

3-(2-CHLORO-PHENYL)-PYRROLIDINE
298690-74-1
US $1.00 / KG
99%
Career Henan Chemical Co

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2-(3-CHLOROPHENYL)PYRROLIDINE AKOS BB-8867 CHEMBRDG-BB 4006410 Pyrrolidine, 2-(3-chlorophenyl)- (+/-)-2-(3-chlorophenyl)-pyrrolidine 298690-74-1