Pertuzumab
- CAS No.
- 380610-27-5
- Chemical Name:
- Pertuzumab
- Synonyms
- 2C4;Omnitarg;pertuzumab;Unii-K16aiq8ctm;Pertuzumab-Perjeta;Pertuzumab (anti-HER2);Research Grade Pertuzumab(DHC09602);Immunoglobulin G1, anti-(human V (receptor)) (human-mouse monoclonal 2C4 heavy chain), disulfide with human-mouse monoclonal 2C4 kappa-chain, dimer
- CBNumber:
- CB41856062
- Molecular Formula:
- C17H27NO2
- Molecular Weight:
- 277.40178
- MDL Number:
- MFCD08436787
- MOL File:
- 380610-27-5.mol
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | K16AIQ8CTM |
| NCI Dictionary of Cancer Terms | pertuzumab |
| NCI Drug Dictionary | pertuzumab |
| ATC code | L01XC13 |
| Proposition 65 List | Pertuzumab |
SAFETY
Risk and Safety Statements
| Hazardous Substances Data | 380610-27-5(Hazardous Substances Data) |
|---|
Pertuzumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-7826 | Pertuzumab | 380610-27-5 | 1mg | $348 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BP165593 | Pertuzumab | 380610-27-5 | 1mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-7826 | Pertuzumab | 380610-27-5 | 5mg | $705 | 2021-12-16 | Buy |
| ChemScene | CS-7826 | Pertuzumab | 380610-27-5 | 25mg | $2650 | 2021-12-16 | Buy |
| ChemScene | CS-7826 | Pertuzumab | 380610-27-5 | 50mg | $4250 | 2021-12-16 | Buy |
Pertuzumab Chemical Properties,Uses,Production
Description
Pertuzumab is an anti-human epidermal growth factor receptor 2 (HER2) antibody that was approved by the US FDA in June 2012 for use in combination with trastuzumab (Herceptin?) and docetaxel chemotherapy for the treatment of people with HER2-positive (HER2+) metastatic breast cancer (mBC) who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease. Pertuzumab inhibits HER2 dimer formation with other HER members, such as HER1 and HER3, thus inhibiting the downstream signaling processes associated with tumor growth and progression. Pertuzumab is the first HER2 dimerization inhibitor to reach the market. The mechanism of actions of trastuzumab and pertuzumab are believed to complement each other and provide a more comprehensive inhibition of tumor growth than either agent alone. Preclinical data showed that the combination of trastuzumab and pertuzumab has a strongly enhanced antitumor effect and induces tumor regression in xenograft models, something that cannot be achieved by either monotherapy alone.
Originator
Genentech, a member of the Roche Group (United States)
Uses
Anti-neoplastic.
brand name
Perjeta
Clinical Use
Monoclonal antibody:
Treatment of HER2 receptor +ve breast cancer
Metabolism
Antibodies are cleared mainly by catabolism.
Pertuzumab Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| Shanghai Minbiotech Co., Ltd. | +8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49978 | 58 |
View Lastest Price from Pertuzumab manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-09-16 | Pertuzumab
380610-27-5
|
US $0.00-0.00 / mg | 5mg | 99% | 50KG | Hangzhou Huarong Pharm Co., Ltd. | |
 |
2020-01-03 | Pertuzumab
380610-27-5
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Pertuzumab
380610-27-5
- US $0.00-0.00 / mg
- 99%
- Hangzhou Huarong Pharm Co., Ltd.
-
- Pertuzumab
380610-27-5
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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