11-Aminoundecanoic acid
- CAS No.
- 2432-99-7
- Chemical Name:
- 11-Aminoundecanoic acid
- Synonyms
- nci-c50613;H-11-Aun-OH;NH2-(CH2)10-COOH;ω-aminoundecanoic;11-Aminoundecansure;aminoundecanoicacid;11-Aminoundecanoic a;11-Amino-undecansaeure;11-amino-undecanoicaci;11-AMINOUNDECYLIC ACID
- CBNumber:
- CB4187611
- Molecular Formula:
- C11H23NO2
- Molecular Weight:
- 201.31
- MDL Number:
- MFCD00008150
- MOL File:
- 2432-99-7.mol
- MSDS File:
- SDS
| Melting point | 188-191 °C (lit.) |
|---|---|
| Boiling point | 339.24°C (rough estimate) |
| Density | 0.9896 (rough estimate) |
| refractive index | 1.4420 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | 2g/l |
| form | Crystalline Powder |
| pka | 4.78±0.10(Predicted) |
| color | White |
| Water Solubility | 2 g/L (20 ºC) |
| BRN | 1767291 |
| InChIKey | GUOSQNAUYHMCRU-UHFFFAOYSA-N |
| LogP | -0.16 at 20℃ |
| CAS DataBase Reference | 2432-99-7(CAS DataBase Reference) |
| Indirect Additives used in Food Contact Substances | 11-AMINOUNDECANOIC ACID |
| EWG's Food Scores | 1 |
| FDA UNII | SFU34976HB |
| IARC | 3 (Vol. 39, Sup 7) 1987 |
| EPA Substance Registry System | 11-Aminoundecanoic acid (2432-99-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Risk Statements | 52 |
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | YQ2293000 |
| HS Code | 29224995 |
| Toxicity | LDLo orl-rat: 14,700 mg/kg NTPTR* NTP-TR-216,82 |
11-Aminoundecanoic acid price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A82605 | 11-Aminoundecanoic acid 97% | 2432-99-7 | 100g | $67.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | A82605 | 11-Aminoundecanoic acid 97% | 2432-99-7 | 500g | $212 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.01228 | 11-Aminoundecanoic acid for synthesis | 2432-99-7 | 250g | $171 | 2024-03-01 | Buy |
| TRC | A633210 | 11-Aminoundecanoic acid | 2432-99-7 | 250g | $185 | 2021-12-16 | Buy |
| TRC | A633210 | 11-Aminoundecanoic acid | 2432-99-7 | 1000g | $580 | 2021-12-16 | Buy |
11-Aminoundecanoic acid Chemical Properties,Uses,Production
Description
Aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Aminoundecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Chemical Properties
White crystalline powder
Chemical Properties
11-Aminoundecanoic acid is a solid.
Uses
11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1''as matrix metalloproteinase inhibitors.
Definition
ChEBI: 11-Aminoundecanoic acid is a medium-chain fatty acid.
Preparation
|?-Aminoundecanoic acid is normally prepared from castor oil (glycerol
triricinoleate). Firstly the castor oil is subjected to methanolysis to yield the
methyl ester of ricinoleic acid and then the following route is used:
In the first step, the pyrolysis of methyl ricinoleate is carried out at about 500??C; the principal products are n-heptaldehyde and methyl undecylenate. The latter is hydrolysed to give undecylenic acid which is treated with hydrogen bromide in a non-polar solvent in the presence of a peroxide. Under these conditions, reverse Markownikoff addition occurs and the main product is |?-bromoundecanoic acid. This product is then treated with ammonia to give |?-aminoundecanoic acid, which is a crystalline solid, m.p. 189??C.
General Description
White crystalline solid or powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
11-Aminoundecanoic acid is incompatible with strong oxidizing agents, strong acids and strong bases.
Fire Hazard
Flash point data for 11-Aminoundecanoic acid are not available; however, 11-Aminoundecanoic acid is probably combustible.
Flammability and Explosibility
Non flammable
Safety Profile
Poison by ingestion. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
11-Aminoundecanoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5978 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18777 | 58 |
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 | sales@thbiochem.com | CHINA | 305 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2993 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
View Lastest Price from 11-Aminoundecanoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | 11-Aminoundecanoic acid
2432-99-7
|
US $0.00 / Kg/Drum | 1KG | 99%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-07-02 | 11-Aminoundecanoic acid 97%
2432-99-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2020-01-08 | 11-Aminoundecanoic acid
2432-99-7
|
US $1.00 / g | 1g | 99.0% | 100kg | Career Henan Chemical Co |
-
- 11-Aminoundecanoic acid
2432-99-7
- US $0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 11-Aminoundecanoic acid 97%
2432-99-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 11-Aminoundecanoic acid
2432-99-7
- US $1.00 / g
- 99.0%
- Career Henan Chemical Co
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