|?-Aminoundecanoic acid is normally prepared from castor oil (glycerol
triricinoleate). Firstly the castor oil is subjected to methanolysis to yield the
methyl ester of ricinoleic acid and then the following route is used:
In the first step, the pyrolysis of methyl ricinoleate is carried out at about
500??C; the principal products are n-heptaldehyde and methyl undecylenate.
The latter is hydrolysed to give undecylenic acid which is treated with
hydrogen bromide in a non-polar solvent in the presence of a peroxide.
Under these conditions, reverse Markownikoff addition occurs and the main
product is |?-bromoundecanoic acid. This product is then treated with
ammonia to give |?-aminoundecanoic acid, which is a crystalline solid, m.p.
189??C.
일반 설명
White crystalline solid or powder.
공기와 물의 반응
Insoluble in water.
반응 프로필
11-Aminoundecanoic acid is incompatible with strong oxidizing agents, strong acids and strong bases.
화재위험
Flash point data for 11-Aminoundecanoic acid are not available; however, 11-Aminoundecanoic acid is probably combustible.
Safety Profile
Poison by ingestion. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
