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(+)-trans-Tramadol free base

CAS No.
123154-38-1
Chemical Name:
(+)-trans-Tramadol free base
Synonyms
(1R-cis)-;(+)-Tramadol;(R,R)-tramadol;(+)-trans-Tramadol free base;Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-
CBNumber:
CB42129475
Molecular Formula:
C16H25NO2
Molecular Weight:
263.38
MDL Number:
MOL File:
123154-38-1.mol
Last updated:2023-05-04 17:34:32

(+)-trans-Tramadol free base Properties

storage temp. Refrigerator
FDA UNII 0NG5TTM63P

(+)-trans-Tramadol free base Chemical Properties,Uses,Production

Chemical Properties

(+)-trans-Tramadol free base is Light Yellow Oil

Uses

(+)-trans-Tramadol free base is an analgesic. Used in the treatment of urinary incontinence.

Definition

ChEBI: (R,R)-tramadol is a 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have R-configuration; the (R,R)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a nicotinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist, a serotonin uptake inhibitor and a metabolite. It is a conjugate base of a (R,R)-tramadol(1+). It is an enantiomer of a (S,S)-tramadol.

(+)-trans-Tramadol free base Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-trans-Tramadol free base (+)-Tramadol (1R-cis)- (R,R)-tramadol Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)- 123154-38-1 Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals