(+)-trans-Tramadol free base
- CAS No.
- 123154-38-1
- Chemical Name:
- (+)-trans-Tramadol free base
- Synonyms
- (1R-cis)-;(+)-Tramadol;(R,R)-tramadol;(+)-trans-Tramadol free base;Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-
- CBNumber:
- CB42129475
- Molecular Formula:
- C16H25NO2
- Molecular Weight:
- 263.38
- MDL Number:
- MOL File:
- 123154-38-1.mol
storage temp. | Refrigerator |
---|---|
FDA UNII | 0NG5TTM63P |
(+)-trans-Tramadol free base Chemical Properties,Uses,Production
Chemical Properties
(+)-trans-Tramadol free base is Light Yellow Oil
Uses
(+)-trans-Tramadol free base is an analgesic. Used in the treatment of urinary incontinence.
Definition
ChEBI: (R,R)-tramadol is a 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have R-configuration; the (R,R)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a nicotinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist, a serotonin uptake inhibitor and a metabolite. It is a conjugate base of a (R,R)-tramadol(1+). It is an enantiomer of a (S,S)-tramadol.