Vadocaine hydrochloride
- CAS No.
- Chemical Name:
- Vadocaine hydrochloride
- Synonyms
- Vadocaine hydrochloride
- CBNumber:
- CB42430487
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Vadocaine hydrochloride Chemical Properties,Uses,Production
Originator
Vadocaine hydrochloride ,ZYF Pharm Chemical
Manufacturing Process
3-Chloro-4',6'-dimethyl-o-propananisidide was prepared by using 92.8 g (0.615 mol) 4,6-dimethyl-o-anisidine and 86 g (0.68 mol) of 3-chloropropionyl chloride, melting point 123-125°C. A mixture containing 40 g (0.165 mol) of 3-chloro-4',6'-dimethyl-o-propananisidide, 54.3 g of 3-methyl piperidine, and 330 ml of anhydrous benzene was heated for 72 hours at 65°C. 47.7 g (84.5%) of N-(2-methoxy-4,6-dimethylphenyl)-2-methyl-1- piperidinepropanamide hydrochloride was obtained by deposition of product in anhydrous acetone saturated with hydrogen chloride; melting point 192-193°C (crystallization from a mixture isopropanol-acetone).
Therapeutic Function
Antitussive, Local anesthetic
Vadocaine hydrochloride Preparation Products And Raw materials
Vadocaine hydrochloride