3,6-dibromopyrazin-2-amine
- CAS No.
- 957230-70-5
- Chemical Name:
- 3,6-dibromopyrazin-2-amine
- Synonyms
- 3,6-DIBROMOPYRAZIN-2-AMINE;3,6-dibromo-2-pyrazinamine;3,6-didroMopyrazin-2-aMine;2-aMino-3,6-DibroMopyrazine;2,5-Dibromo-3-aminopyrazine;3,6-Dibromopyrazine-2-amine;3-Amino-2,5-dibromopyrazine;2-Pyrazinamine, 3,6-dibromo-;3,6-Dibromopyrazin-2-ylamine;3,6-DIBROMOPYRAZIN-2-AMIN...
- CBNumber:
- CB42455291
- Molecular Formula:
- C4H3Br2N3
- Molecular Weight:
- 252.89
- MDL Number:
- MFCD11040377
- MOL File:
- 957230-70-5.mol
- MSDS File:
- SDS
Boiling point | 314℃ |
---|---|
Density | 2.287 |
Flash point | 144℃ |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
pka | 0.05±0.10(Predicted) |
Water Solubility | Slightly soluble in water. |
InChI | InChI=1S/C4H3Br2N3/c5-2-1-8-3(6)4(7)9-2/h1H,(H2,7,9) |
InChIKey | ZEDFFSRZLCREEN-UHFFFAOYSA-N |
SMILES | C1(N)=NC(Br)=CN=C1Br |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
NFPA 704 |
|
3,6-dibromopyrazin-2-amine price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alfa Aesar | H59185 | 2-Amino-3,6-dibromopyrazine, 95% | 957230-70-5 | 1g | $337 | 2022-04-27 | Buy |
Alfa Aesar | H59185 | 2-Amino-3,6-dibromopyrazine, 95% | 957230-70-5 | 250mg | $105 | 2021-12-16 | Buy |
TRC | D424740 | 3,6-Dibromopyrazin-2-amine | 957230-70-5 | 1g | $75 | 2021-12-16 | Buy |
Matrix Scientific | 068899 | 3,6-Dibromopyrazin-2-amine >95% | 957230-70-5 | 250mg | $171 | 2021-12-16 | Buy |
Matrix Scientific | 068899 | 3,6-Dibromopyrazin-2-amine >95% | 957230-70-5 | 1g | $429 | 2021-12-16 | Buy |
3,6-dibromopyrazin-2-amine Chemical Properties,Uses,Production
Uses
It is used as a pharmaceutical intermediate.
Synthesis
Diphenylphosphoryl azide (488 mg, 1.77 mmol) and triethylamine (180 mg, 1.77 mmol) were added to a solution of the acid (500 mg, 1.77 mmol) in tert-butanol (12 mL). The reaction mixture was stirred at reflux for 18 h and then quenched with water. The volatiles were removed under reduced pressure. The residue was dissolved in 4:1 TFA/DCM (5 mL) and stirred at rt for 1 h. The volatiles were removed under reduced pressure. The residue was dissolved in DCM and washed with 1N aq. NaOH. The combined organic extracts were dried (Na2SO4), filtered and concentrated. The crude residue was purified by SiO2 chromatography eluting with an EtOAc/hexane gradient to afford 3,6-dibromopyrazin-2-amine 120 mg (27%) of bromoanisol as a colorless oil. MS m/z (ES): 253 (M+H)+.
3,6-dibromopyrazin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29821 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 13234 | 58 |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
View Lastest Price from 3,6-dibromopyrazin-2-amine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-01-08 | 3,6-DIBROMOPYRAZIN-2-AMINE
957230-70-5
|
US $2.00 / KG | 1KG | 99 | 100kg | Career Henan Chemical Co |
- 3,6-DIBROMOPYRAZIN-2-AMINE
957230-70-5
- US $2.00 / KG
- 99
- Career Henan Chemical Co