ChemicalBook >> CAS DataBase List >>FR901464
FR901464
- CAS No.
- 146478-72-0
- Chemical Name:
- FR901464
- Synonyms
- WB 2663B;FR901464;PJKVJJDQXZARCA-QHYZBLTGSA-N;FR 901464|||FR-901464|||WB 2663B;(2S,3Z)-4-{[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]-3-methylpenta-2,4-dien-1-yl]-2,5-dimethyloxan-3-yl]carbamoyl}but-3-en-2-yl acetate;2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]tetrahydro-2,5-dimethyl-2H-pyran-3-yl]-, (2Z,4S)-
- CBNumber:
- CB42627890
- Molecular Formula:
- C27H41NO8
- Molecular Weight:
- 507.62
- MDL Number:
- MFCD27665477
- MOL File:
- 146478-72-0.mol
Last updated:2025-01-27 09:38:02
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO : 100 mg/mL (197.00 mM; Need ultrasonic) |
| form | Solid |
| color | White to off-white |
| EWG's Food Scores | 1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
FR901464 Chemical Properties,Uses,Production
Description
FR901464 is a potent anticancer moecule that lowers the mRNA levels of oncogenes and tumor suppressor genes.
Definition
ChEBI: A spiro-epoxide with potent anticancer activity that lowers the mRNA levels of oncogenes and tumour supressor genes. It is isolated from Pseudomonas sp. no.2663.
Synthesis of FR901464 from 1,6-Dioxaspiro[2.5]octane-4,7-diol, 5-ethenyl-7-methyl-, (3R,4R,5R,7S)- and 2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E)-3-methyl-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)-
FR901464 Preparation Products And Raw materials
FR901464 Suppliers
Global( 49)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10319 | 58 |
| Shanghai Minbiotech Co., Ltd. | +8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15350 | 58 |
| Henan Alfa Chemical Co., Ltd | China | 13179 | 58 | ||
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
FR901464
WB 2663B
PJKVJJDQXZARCA-QHYZBLTGSA-N
2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]tetrahydro-2,5-dimethyl-2H-pyran-3-yl]-, (2Z,4S)-
FR 901464|||FR-901464|||WB 2663B
(2S,3Z)-4-{[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]-3-methylpenta-2,4-dien-1-yl]-2,5-dimethyloxan-3-yl]carbamoyl}but-3-en-2-yl acetate
146478-72-0