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ChemicalBook >> CAS DataBase List >>2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1)

2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1)

2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) Structure
2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) structure
CAS No.
1165923-54-5
Chemical Name:
2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1)
Synonyms
GSK2262167;GSK 2262167;GSK-2262167;GSK-2262167 sodium;LCIDCFMLDWPFGR-UHFFFAOYSA-N;GSK 2262167 sodium,GSK2262167 sodium;2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1)
CBNumber:
CB42668556
Molecular Formula:
C25H27N4NaO4
Molecular Weight:
470.5
MDL Number:
MFCD25977117
MOL File:
1165923-54-5.mol
Last updated:2023-03-31 09:12:58
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2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) Chemical Properties,Uses,Production

Description

GSK-2262167 is a potent S1P3-sparing and orally active S1P1 agonist. CGSK-2262167 is as efficacious as fingolimod in a collagen-induced arthritis model and shows excellent pharmacokinetic properties preclinically. Importantly, the selectivity of GSK-2262167 against S1P3 is responsible for an absence of cardiovascular signal in telemetered rats, even at high dose levels.

2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 58
2(1H)-Isoquinolinepropanoic acid,6-[5-[3-cyano-4-(1-Methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-3,4-dihydro-5-Methyl-,sodiuM salt(1:1) GSK-2262167 sodium GSK-2262167 GSK2262167 GSK 2262167 LCIDCFMLDWPFGR-UHFFFAOYSA-N GSK 2262167 sodium,GSK2262167 sodium 1165923-54-5 458576-13-0