2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
- CAS No.
- 56701-24-7
- Chemical Name:
- 2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
- Synonyms
- VESTITOL;DL-Vestitol;(±)-Vestitol;(+/-)-Vestitol;VESTITOL(RG)(PLEASE CALL);2',7-DIHYDROXY-4'-METHOXYISOFLAVAN;3-(2-Hydroxy-4-methoxyphenyl)-7-chromanol;3-(2-Hydroxy-4-methoxyphenyl)chroman-7-ol;3-（2-Hydroxy-4-Methoxyphenyl）-3,4-Dihydro-2H-Chromen-7-Ol;3-(2-Hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
- CBNumber:
- CB4268611
- Molecular Formula:
- C16H16O4
- Molecular Weight:
- 272.3
- MDL Number:
- MFCD00075893
- MOL File:
- 56701-24-7.mol
| Melting point | 172-179℃ |
|---|---|
| Boiling point | 418.5±45.0 °C(Predicted) |
| Density | 1.282±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: 2mg/mL, clear |
| pka | 9.53±0.40(Predicted) |
| form | powder |
| color | white to beige |
| FDA UNII | Z244UVZ669 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN price
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Chemical Properties,Uses,Production
Uses
Vestitol is the compound isolated from leaves of Trifolium arvense[1].
Definition
ChEBI: Vestitol is a member of the class of hydroxyisoflavans that is isoflavan substituted by hydroxy groups at positions 7 and 2' and a methoxy group at position 4'. Isolated from Glycyrrhiza uralensis, it exhibits anti-inflammatory activity. It has a role as an anti-inflammatory agent, a plant metabolite and a phytoalexin. It is an aromatic ether, a member of hydroxyisoflavans and a methoxyisoflavan.
Biological Activity
Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities.
(±)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolis, licorice root and other sources th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml).
References
[1] John L. Ingham, et al. Notizen: Isoflavonoid Phytoalexins from Leaves of Trifolium arvense.
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Preparation Products And Raw materials
Raw materials
Preparation Products
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Suppliers
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