Optovin
- CAS No.
- 348575-88-2
- Chemical Name:
- Optovin
- Synonyms
- CS-1131;Oprovin;Optovin;Optovin (mixture of isomers);5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone;5-((2,5-Dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one;4-Thiazolidinone, 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-
- CBNumber:
- CB42708133
- Molecular Formula:
- C15H13N3OS2
- Molecular Weight:
- 315.41
- MDL Number:
- MFCD02219276
- MOL File:
- 348575-88-2.mol
| Density | 1.38±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Soluble in DMSO (up to 30 mg/ml) |
| form | solid |
| pka | 7.65±0.50(Predicted) |
| color | Tan |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Optovin price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14851 | Optovin ≥98% | 348575-88-2 | 5mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 14851 | Optovin ≥98% | 348575-88-2 | 10mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 14851 | Optovin ≥98% | 348575-88-2 | 25mg | $317 | 2024-03-01 | Buy |
| Cayman Chemical | 14851 | Optovin ≥98% | 348575-88-2 | 50mg | $553 | 2024-03-01 | Buy |
| Tocris | 4901 | Optovin ≥99%(HPLC) | 348575-88-2 | 50 | $767 | 2021-12-16 | Buy |
Optovin Chemical Properties,Uses,Production
Description
Optovin (348575-88-2) is a reversible photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50?= 2 μM) and mice,?in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1
Uses
Optovin activates human TRPA1 via structure-dependent photochemistry.
Definition
ChEBI: Optovin is a member of the class of thiazolidinone that is rhodanine in which the two methylene hydrogens have been replaced by a 2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl]methylidene group. A TRPA1 ligand that can be reversibly photoactivated. It has a role as a TRPA1 channel agonist. It is a member of pyrroles, a member of pyridines, an olefinic compound and a thiazolidinone. It is functionally related to a rhodanine.
storage
Store at +4°C
References
1) Kokel?et al. (2013),?Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol.,?9?257
Optovin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9314 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from Optovin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Optovin
348575-88-2
|
US $34.00-74.00 / mg | 99.16% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-07-13 | Optovin
348575-88-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-10 | Optovin
348575-88-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |