ML-228
- CAS No.
- 1357171-62-0
- Chemical Name:
- ML-228
- Synonyms
- L-228;ML-228;CID-46742353;ML228; ML 228;ML-228;CID-46742353;ML228, 10 mM in DMSO;N-([1,1'Biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine;N-([1,1-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine;1,2,4-Triazin-5-amine, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-
- CBNumber:
- CB42744612
- Molecular Formula:
- C27H21N5
- Molecular Weight:
- 415.49
- MDL Number:
- MFCD26792570
- MOL File:
- 1357171-62-0.mol
ML-228 price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14568 | ML-228 ≥95% | 1357171-62-0 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 14568 | ML-228 ≥95% | 1357171-62-0 | 5mg | $131 | 2024-03-01 | Buy |
| Cayman Chemical | 14568 | ML-228 ≥95% | 1357171-62-0 | 10mg | $230 | 2024-03-01 | Buy |
| Cayman Chemical | 14568 | ML-228 ≥95% | 1357171-62-0 | 50mg | $987 | 2024-03-01 | Buy |
| Tocris | 4565 | ML228 ≥98%(HPLC) | 1357171-62-0 | 50 | $992 | 2021-12-16 | Buy |
ML-228 Chemical Properties,Uses,Production
Uses
N-([1,1''-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine is an activator of the hypoxia inducible factor (HIF) pathway.
Definition
ChEBI: ML228 is a member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. It has a role as a hypoxia-inducible factor pathway activator. It is a member of biphenyls, a member of 1,2,4-triazines, a secondary amino compound and a member of pyridines.
in vivo
ML228 (injection; 1 μg/kg; 7 days) treatments following spinal cord injury (SCI) improves the local hypoxic ischemia environment, reduce SCI secondary injury and promote the recovery of neurological function[3].
| Animal Model: | SD rat[3] |
| Dosage: | 1 μg/kg |
| Administration: | injection; 7 days |
| Result: | Alleviated SCI of the central nervous system and relieve associated symptoms. |
ML-228 Preparation Products And Raw materials
Raw materials
Preparation Products
ML-228 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 |
