ChemicalBook >> CAS DataBase List >>Fezolinetant
Fezolinetant
- CAS No.
- 1629229-37-3
- Chemical Name:
- Fezolinetant
- Synonyms
- ESN-364;Fezolinetant;Fexolinetant;FEZOLINETANT; ESN-364; ESN 364; ESN364;Inhibitor,Neurokinin Receptor,ESN364,Tachykinin receptor,ESN 364,Fezolinetant,inhibit,NK receptor;(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone;Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
- CBNumber:
- CB43159873
- Molecular Formula:
- C16H15FN6OS
- Molecular Weight:
- 358.39
- MDL Number:
- MFCD30532641
- MOL File:
- 1629229-37-3.mol
Last updated:2024-07-18 18:48:45
| Boiling point | 623.0±65.0 °C(Predicted) |
|---|---|
| Density | 1.56±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:20.0(Max Conc. mg/mL);55.8(Max Conc. mM) |
| pka | -0.28±0.40(Predicted) |
| form | Solid |
| color | White to yellow |
| InChI | InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1 |
| InChIKey | PPSNFPASKFYPMN-SECBINFHSA-N |
| SMILES | C(N1CCN2C(C3SN=C(C)N=3)=NN=C2[C@H]1C)(C1=CC=C(F)C=C1)=O |
| FDA UNII | 83VNE45KXX |
Fezolinetant price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-7952 | Fezolinetant 98.16% | 1629229-37-3 | 1mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-7952 | Fezolinetant 98.16% | 1629229-37-3 | 5mg | $390 | 2021-12-16 | Buy |
| ChemScene | CS-7952 | Fezolinetant 98.16% | 1629229-37-3 | 10mg | $570 | 2021-12-16 | Buy |
| ChemScene | CS-7952 | Fezolinetant 98.16% | 1629229-37-3 | 25mg | $1140 | 2021-12-16 | Buy |
| ChemScene | CS-7952 | Fezolinetant 98.16% | 1629229-37-3 | 50mg | $1740 | 2021-12-16 | Buy |
Fezolinetant Chemical Properties,Uses,Production
Uses
Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes.
Definition
ChEBI: Fezolinetant is a triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. It has a role as a neurokinin-3 receptor antagonist. It is a member of monofluorobenzenes, a triazolopyrazine, a member of thiadiazoles, a member of benzamides and a tertiary carboxamide.
Fezolinetant Preparation Products And Raw materials
Raw materials
Preparation Products
Fezolinetant Suppliers
Global( 85)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd. | +86-0311-67591193 +8613931880626 | sales02@dingminpharma.com | China | 238 | 58 |
| Jinan Million Pharmaceutical Co., Ltd | +86-531-68659554 +8613031714605 | info@millionpharm.com | China | 191 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7353 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 13141 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Chemtour Biotech Co., Ltd | +8617327281506 | market@chemtour.com | China | 1460 | 58 |
| TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 | yuxin@yuxchem.com | China | 158 | 58 |
View Lastest Price from Fezolinetant manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-26 | Birinapant
1629229-37-3
|
US $1.00-0.50 / kg | 1kg | 99% | 200 | Jinan Million Pharmaceutical Co., Ltd | |
 |
2024-07-19 | Fezolinetant
1629229-37-3
|
US $0.00 / g | 1g | More Than 99% | 50kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. |
-
- Birinapant
1629229-37-3
- US $1.00-0.50 / kg
- 99%
- Jinan Million Pharmaceutical Co., Ltd
-
- Fezolinetant
1629229-37-3
- US $0.00 / g
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
ESN-364
FEZOLINETANT; ESN-364; ESN 364; ESN364
Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
Inhibitor,Neurokinin Receptor,ESN364,Tachykinin receptor,ESN 364,Fezolinetant,inhibit,NK receptor
(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
Fexolinetant
Fezolinetant
1629229-37-3
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