Fezolinetant manufacturers
- Birinapant
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- $1.00 / 1kg
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2024-07-26
- CAS:1629229-37-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 200
- Fezolinetant
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- $0.00 / 1g
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2024-07-19
- CAS:1629229-37-3
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 50kg/Month
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| Fezolinetant Basic information |
Product Name: | Fezolinetant | Synonyms: | ESN-364;FEZOLINETANT; ESN-364; ESN 364; ESN364;Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-;Inhibitor,Neurokinin Receptor,ESN364,Tachykinin receptor,ESN 364,Fezolinetant,inhibit,NK receptor;(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone;Fexolinetant;Fezolinetant | CAS: | 1629229-37-3 | MF: | C16H15FN6OS | MW: | 358.39 | EINECS: | | Product Categories: | APIS;API | Mol File: | 1629229-37-3.mol | ![Fezolinetant Structure](CAS/20200611/GIF/1629229-37-3.gif) |
| Fezolinetant Chemical Properties |
Boiling point | 623.0±65.0 °C(Predicted) | density | 1.56±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO:20.0(Max Conc. mg/mL);55.8(Max Conc. mM) | pka | -0.28±0.40(Predicted) | form | Solid | color | White to yellow | InChI | InChI=1S/C16H15FN6OS/c1-9-13-19-20-14(15-18-10(2)21-25-15)23(13)8-7-22(9)16(24)11-3-5-12(17)6-4-11/h3-6,9H,7-8H2,1-2H3/t9-/m1/s1 | InChIKey | PPSNFPASKFYPMN-SECBINFHSA-N | SMILES | C(N1CCN2C(C3SN=C(C)N=3)=NN=C2[C@H]1C)(C1=CC=C(F)C=C1)=O |
| Fezolinetant Usage And Synthesis |
Uses | Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. | Definition | ChEBI: Fezolinetant is a triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. It has a role as a neurokinin-3 receptor antagonist. It is a member of monofluorobenzenes, a triazolopyrazine, a member of thiadiazoles, a member of benzamides and a tertiary carboxamide. |
| Fezolinetant Preparation Products And Raw materials |
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