NIGERICIN SODIUM SALT
- CAS No.
- 28380-24-7
- Chemical Name:
- NIGERICIN SODIUM SALT
- Synonyms
- x-464;Helix c;HELIXIN C;NIGERICIN;Aids003767;Aids-003767;AZALOMYCIN M;NIGERICIN NA;POLYETHERIN A;Antibiotic M 2
- CBNumber:
- CB4331016
- Molecular Formula:
- C40H68O11
- Molecular Weight:
- 724.96
- MDL Number:
- MFCD00036825
- MOL File:
- 28380-24-7.mol
Melting point | 183.5-185° |
---|---|
alpha | D24 +36.2° (c = 0.842 in CHCl3) |
Boiling point | 779.9±60.0 °C(Predicted) |
Density | 1.19±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | chloroform: 10 mg/mL, clear, colorless |
pka | 4.39±0.10(Predicted) |
EWG's Food Scores | 1 |
FDA UNII | RRU6GY95IS |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H319-H335-H301-H315 |
Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Hazard Codes | T,Xi |
Risk Statements | 25-36/37/38 |
Safety Statements | 26-36/37/39-45-36 |
RIDADR | UN 3462 6.1/PG 3 |
WGK Germany | 3 |
RTECS | QT6840000 |
F | 10 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29419090 |
Toxicity | LD50 in mice (mg/kg): 10-15 i.p. (Shoji); also reported as 2.5 i.p. (Harned) |
NIGERICIN SODIUM SALT price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
American Custom Chemicals Corporation | API0003572 | NIGERICIN 95.00% | 28380-24-7 | 5MG | $673.61 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003572 | NIGERICIN 95.00% | 28380-24-7 | 10MG | $686.65 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003572 | NIGERICIN 95.00% | 28380-24-7 | 25MG | $737.58 | 2021-12-16 | Buy |
AvaChem | 2066 | Nigericin | 28380-24-7 | 1g | $3250 | 2021-12-16 | Buy |
AvaChem | 2066 | Nigericin | 28380-24-7 | 5mg | $45 | 2021-12-16 | Buy |
NIGERICIN SODIUM SALT Chemical Properties,Uses,Production
Uses
Nigericin is a polyether antibiotic produced by Streptomyces, notably S. hygroscopicus, isolated in the 1950s. Its complex structure was finally elucidated in 1968. Nigericin is an ionophore, possessing very high affinity for monovalent cations such as Na+ and K+. Nigericin disrupts membrane potential and Golgi apparatus in mitochondria. Although nigericin can be isolated as the free acid (under acidic conditions), like most ionophores it is extracted into organic solvents and is most conveniently isolated as a salt. In vitro, nigericin has broad biological activity against Gram positive bacteria, fungi, tumour cell lines and some viruses, including HIV. Nigericin is the most common member of the polyether class which are common false positives in in vitro screening bioassays using crude microbial extracts. They are thus important standards for dereplication.
Definition
ChEBI: A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus.
NIGERICIN SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
NIGERICIN SODIUM SALT Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 | wendy@huidabiotech.com | CHINA | 87 | 58 |
Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9427 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8079 | 58 |
View Lastest Price from NIGERICIN SODIUM SALT manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2020-01-13 | NIGERICIN SODIUM SALT
28380-24-7
|
US $1.00 / KG | 1KG | 98%-99.9% | 200kg | Career Henan Chemical Co |
-
- NIGERICIN SODIUM SALT
28380-24-7
- US $1.00 / KG
- 98%-99.9%
- Career Henan Chemical Co