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L-Lactide

L-Lactide Structure
L-Lactide structure
CAS No.
4511-42-6
Chemical Name:
L-Lactide
Synonyms
LACTIDE;L-LA;L-(-)-LACTIDE;LL-Lactide;L,L-Dilactide;(3S)-CIS-3,6-DIMETHYL-1,4-DIOXANE-2,5-DIONE;-(-)-L;actide;(3S,6S);L-LACTIDE
CBNumber:
CB4416791
Molecular Formula:
C6H8O4
Molecular Weight:
144.13
MDL Number:
MFCD00070594
MOL File:
4511-42-6.mol
Last updated:2025-04-23 09:18:07
Request For Quotation

L-Lactide Properties

Melting point 92-94 °C(lit.)
Boiling point 255°C
Density 1.186±0.06 g/cm3(Predicted)
vapor pressure 0.311Pa at 25℃
refractive index 1.4475
storage temp. 2-8°C
solubility Soluble in chloroform, and methanol. Slightly soluble in benzene.
form Solid
color White to Off-White
optical activity [α]20/D 285°, c = 1 in toluene
Water Solubility 16.7g/L at 20℃
Sensitive Moisture Sensitive
BRN 82124
Stability Hygroscopic
InChIKey JJTUDXZGHPGLLC-IMJSIDKUSA-N
LogP 0.4 at 25℃
CAS DataBase Reference 4511-42-6(CAS DataBase Reference)
FDA UNII IJ13TO4NO1
EPA Substance Registry System 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)- (4511-42-6)
UNSPSC Code 12352005
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-36
Safety Statements  26-37/39
WGK Germany  3
TSCA  Yes
HS Code  29322090
NFPA 704
1
2 0

L-Lactide price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 367044 (3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione 98% 4511-42-6 25g $88.1 2024-03-01 Buy
Sigma-Aldrich 367044 (3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione 98% 4511-42-6 100g $307 2024-03-01 Buy
TCI Chemical L0115 L-(-)-Lactide >98.0%(T) 4511-42-6 25g $93 2024-03-01 Buy
TCI Chemical L0115 L-(-)-Lactide >98.0%(T) 4511-42-6 250g $557 2024-03-01 Buy
Alfa Aesar L09031 L-Lactide, 98+% 4511-42-6 5g $27.65 2024-03-01 Buy
Product number Packaging Price Buy
367044 25g $88.1 Buy
367044 100g $307 Buy
L0115 25g $93 Buy
L0115 250g $557 Buy
L09031 5g $27.65 Buy

L-Lactide Chemical Properties,Uses,Production

Description

L-lactide (3,6-dimethyl-1,4-dioxane-2,5-dione) is a cyclic lactone that is derived from lactic acid. It has the molecular formula C3H6O2 and is an essential building block for synthesizing polylactic acid (PLA) plastics, which are widely used in the manufacturing industry.

Chemical Properties

White crystal

Uses

(3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione may be used in the synthesis of optically active terpyridine containing poly(L-lactide)s, polydisperse lactic acid oligomers, bicyclic and tricyclic lactide derivatives.

Application

L-Lactide is a monomer used to produce polylactic acid (PLA), which is a biodegradable thermoplastic that has many uses in the pharmaceutical industry. Additionally, L-Lactide can be used to modify existing drug carriers or create new ones from scratch. As such, the pharmaceutical industry relies heavily on L-Lactide for its versatile applications.

Flammability and Explosibility

Non flammable

Purification Methods

This is the cyclic dilactone of lactic acid. The (±)-cis-racemate has been distilled with b 142o/8mm; the distillate which solidifies gives yellow needles on recrystallisation from EtOH with m 128o, from Et2O with m 129o, or CHCl3 with m 126o , 1720-1740 cm-1. It hydrolyses in cold max H2O. [Carothers et al. J Am Chem Soc 54 772 1932]. A trans-form (probably RS,SR) has been reported which crystallises from Et2O with m 42-43o [Hummel et al. Acta Cryst (Sect B) 38 1679 1982]. The R,R -(+)-lactide has b 150o/2mm and crystallises from Et2O with m 95o , or m 96.5 -97.5o (from CHCl3) or m 97.7o (from EtOAc) and [] D +297o (c 1.2, *C6H6). The S,S-(-)-lactide has b 150o/2.5mm and crystallises from EtOAc with m 98.7o, or m 95o (from CHCl3) or m 96.5-97.5o (from CCl4) and []D -297o (c 1.2, *C6H6). [Toniolo et al. J Org Chem 35 6 1970, Beilstein 19 H 154, 19 I 179, 19 II 176, 19 IV 1927, 19/5 V 10.]

L-Lactide synthesis

79-33-4
4511-42-6
Synthesis of L-Lactide from L(+)-Lactic acid

L-Lactide Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl lactate Butyl lactate

L-Lactide Suppliers

Global( 315)Suppliers
Supplier Tel Email Country ProdList Advantage
CD Chemical Group Limited
+8615986615575 info@codchem.com China 20342 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3003 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12809 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531153977 allison@yan-xi.com China 5854 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5868 58
Hebei Fengjia New Material Co., Ltd 		+86-0311-87836622 +86-18712993135 sales01@tairunfaz.com China 8051 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18137 58
Hebei Kingfiner Technology Development Co.Ltd 		+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 3005 58
Hebei Jingbo New Material Technology Co., Ltd 		+8619931165850 hbjbtech@163.com China 1000 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20235 58
Supplier Advantage
CD Chemical Group Limited
58
Shaanxi Dideu Medichem Co. Ltd 		58
Hebei Mujin Biotechnology Co.,Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Fengjia New Material Co., Ltd 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Kingfiner Technology Development Co.Ltd 		58
Hebei Jingbo New Material Technology Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58

Related articles

View Lastest Price from L-Lactide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Lactide pictures 2025-04-25 L-Lactide
4511-42-6
 US $6.00 / kg 1kg 99% 2000KG/Month HebeiShuoshengImportandExportco.,Ltd
L-Lactide pictures 2025-04-24 L-Lactide
4511-42-6
 US $30.00 / kg 1kg 0.99 100 tons Hebei Fengjia New Material Co., Ltd
L-Lactide pictures 2025-04-15 L-Lactide
4511-42-6
 US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
  • L-Lactide pictures
  • L-Lactide
    4511-42-6
  • US $6.00 / kg
  • 99%
  • HebeiShuoshengImportandExportco.,Ltd
  • L-Lactide pictures
  • L-Lactide
    4511-42-6
  • US $30.00 / kg
  • 0.99
  • Hebei Fengjia New Material Co., Ltd
  • L-Lactide pictures
  • L-Lactide
    4511-42-6
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd

L-Lactide Spectrum

L-Lactide(4511-42-6)MSL-Lactide(4511-42-6)1HNMRL-Lactide(4511-42-6)13CNMRL-Lactide(4511-42-6)IR1

4511-42-6(L-Lactide)Related Search:

Dimethyl carbonate Cyclohexane ETHANE Dimethyl sulfoxide Hexane
Dimethyl fumarate Dimethyl ether N,N-Dimethylformamide Cyclohexene oxide Methylcyclohexane
1,4-Dioxane L-Homoserine lactone hydrochloride POLY(D,L-LACTIDE-CO-GLYCOLIDE) LACTIDE(D,L-),DL-LACTIDE,LACTIDE 2-hydroxypropionicacid,isopropylester
1,4-Dioxane-2,5-dione (S)-(-)-2-ACETOXYPROPIONIC ACID ETHYL (S)-(-)-2-METHOXYPROPIONATE

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L-3,6-Dimethyl-1,4-dioxane-2,5-dione 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)- 3,6-dimethyl-1,4-dioxane-2,5-quinone L-(-)-LACTIDE 98+% 3,6-Dimethyl-2,5-p-dioxanedione L-(-)-Lactide ,99% L-3,6-DiMethyl-p-dioxane-2,5-dione L-(-)-Dilactide (3S,6S)-(-)-3,6-Dimethyl-1,4-dioxane-2,5-dione L(-)-Lactide USP (3S)-cis-3,6-DiMethyl-1,4-dioxane-2,5-dione 98% L-(-)-Lactide (3S,6S) (3S,6S)-(-)-3,6-DIMETHYL-1,4-DIOXANE-2,5-DIONE L-LACTIDE S L-LACTIDE LACTIDE(L-) L-(-)-DILACTIDE PURASORB(R) L 5-dione,3,6-dimethyl-,(3s,6s)-4-dioxane-2 (S,S)-3,6-Dimethyl-1,4-dioxane-2,5-dione (3S-cis)-3,6-Dimethyl-1,4-dioxan-2,5-dion -(-)-L Biomaterial Intermediate Monomer L-Lactide (LLA) CAS No.:?4511-42-6 actide L-(-)-Lactide> L-(-)-Dilactide,99%+ L,L-Dilactide LL-Lactide (3S)-CIS-3,6-DIMETHYL-1,4-DIOXANE-2,5-DIONE L-(-)-LACTIDE LACTIDE L-LA Polyhexamethyleneguanidine hydrochloride 57028-96-3 L-lactide/L-lactide (with details) Aaron chemistry (3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione 4511-42-6 4551-42-6 Asymmetric Synthesis Glycidyl Compounds, etc. (Chiral) Lactones & Lactides (for High-Performance Polymer Research) Dioxanes Chiral Building Blocks Dioxanes & Dioxolanes Reagent for High-Performance Polymer Research Organic Building Blocks Lactones Chiral Building Blocks Dioxanes Dioxanes & Dioxolanes Functional Materials Glycidyl Compounds, etc. (Chiral) Lactones & Lactides (for High-Performance Polymer Research) Reagent for High-Performance Polymer Research Synthetic Organic Chemistry 4511-42-6