ChemicalBook >> CAS DataBase List >>Doxifluridine
Doxifluridine
- CAS No.
- 3094-09-5
- Chemical Name:
- Doxifluridine
- Synonyms
- flutron;5'-DFUR;5'DFURD;furtulon;AMC 0101;5-F-5‘-dU;RO-21-9738;5-cl-5'-dU;Doxifluidine;DOXIFLURIDINE
- CBNumber:
- CB4461786
- Molecular Formula:
- C9H11FN2O5
- Molecular Weight:
- 246.19
- MDL Number:
- MFCD00866530
- MOL File:
- 3094-09-5.mol
Last updated:2024-11-19 15:53:33
| Melting point | 188-192 °C(lit.) |
|---|---|
| alpha | D25 +18.4° (c = 0.419 in water) |
| Density | 1.3751 (estimate) |
| refractive index | 20 ° (C=1, H2O) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 7.4(at 25℃) |
| color | White |
| Merck | 14,3437 |
| CAS DataBase Reference | 3094-09-5(CAS DataBase Reference) |
| FDA UNII | V1JK16Y2JP |
| NCI Drug Dictionary | doxifluridine |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P261-P272-P280-P302+P352+P333+P313+P363-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | YU7526000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, IRRITANT-HARMFUL | |||||||||
| HS Code | 29349990 | |||||||||
| Toxicity | LD50 (14 day) in mice or rats (mg/kg): >1000 i.v.: >2000 s.c.; in male, female mice, male, female rats (mg/kg): >5000, >5000, 3471, 3390 orally (Shimizu) | |||||||||
| NFPA 704 |
|
Doxifluridine price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F8791 | 5-Fluoro-5′-deoxyuridine | 3094-09-5 | 25MG | $86.6 | 2023-06-20 | Buy |
| Sigma-Aldrich | Y0001644 | Capecitabine impurity B European Pharmacopoeia (EP) Reference Standard | 3094-09-5 | Y0001644 | $218 | 2023-06-20 | Buy |
| Sigma-Aldrich | F8791 | 5-Fluoro-5′-deoxyuridine | 3094-09-5 | 100MG | $267 | 2023-06-20 | Buy |
| Sigma-Aldrich | F8791 | 5-Fluoro-5′-deoxyuridine | 3094-09-5 | 250MG | $466 | 2023-06-20 | Buy |
| Sigma-Aldrich | PHR2850 | 5′-deoxy-5-fluorouridine certified reference material, pharmaceutical secondary standard | 3094-09-5 | 50MG | $452 | 2022-05-15 | Buy |
Doxifluridine Chemical Properties,Uses,Production
Description
Doxifluridine is a prodrug derivative of 5-fluorouracil (5-FU). As an antineoplastic it is more potent than 5-FU in the treatment of breast, stomach, colon and rectal cancers.
Chemical Properties
White Solid
Originator
Hoffmann-LaRoche (USA)
Uses
antineoplastic, pyrimidine antimetabolite
Uses
A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity
Uses
An antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. A metabolite of Capecitabine
Uses
5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.
Definition
ChEBI: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluoro racil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.
brand name
Furtulon
Biochem/physiol Actions
Doxifluridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts transformed by H-ras or trk oncogenes. Possesses anticachectic activity which is independent of its antiproliferative activity.
Doxifluridine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 356)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3958 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9214 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from Doxifluridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | 5-Fluoro-5′-deoxyuridine
3094-09-5
|
US $0.00 / g | 1g | ≥98.0% | 10kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-19 | Doxifluridine
3094-09-5
|
US $94.00 / g | 99.86% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-08-05 | Doxifluridine
3094-09-5
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-
- 5-Fluoro-5′-deoxyuridine
3094-09-5
- US $0.00 / g
- ≥98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Doxifluridine
3094-09-5
- US $94.00 / g
- 99.86%
- TargetMol Chemicals Inc.
-
- Doxifluridine
3094-09-5
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
3094-09-5(Doxifluridine)Related Search:
5-Fluorouridine
Chenodeoxycholic acid
1-beta-D-Arabinofuranosyluracil
Ursodeoxycholic acid
5-Fluorouracil
DL-PHENYLEPHRINE HYDROCHLORIDE
Trifluridine
Floxuridine
3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine
5'-Deoxy-5-fluorocytidine
1of4
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-pyrimidine-2,4-dione
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl]-5-fluoro-pyrimidine-2,4-quinone
Capecitabine Related Compound B (20 mg) (5'-deoxy-5-fluorouridine)
5μdFUrd, Doxifluridine
5μdFUrd, 5-Fluoro-5μ-deoxyuridine
5’-Deoxy-5-fluomuridine
2,4(1H,3H)-Pyrimidinedione, 1-(5-deoxy-b-D-ribofuranosyl)-5-fluoro-
5Urd, 5-Fluoro-5deoxyuridine
URIDINE,5''-DEOXY-5-FLUORO
1-[(2s,3s,4r,5s)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl]-5-fluoropyrimidine-2,4(1h,3h)-dione
flutron
furtulon
Doxifluridine 3094-9-5
1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
5’dUrd, 5-Fluoro-5’-deoxyuridine, 5’-DFUR, Doxifluridine
5'-dFUrd
Doxifluridine
1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil
Doxifluridine(Ro 21-9738)
CAPECITABINE related substance USP B
RO-21-9738
(+)-5-FLUORO-5'-DEOXYURIDINE
5-FLUORO-5'-DEOXYURIDINE
5'-DEOXY-5-FLUOROURIDINE
5'-DEOXYFLUOROURIDINE
5'-DFUR
5'DFURD
DOXIFLURIDINE
MURINE RECOMBINANT
Doxifluridine (furtulon)
DOXIFLUIRDINE
5'-Deoxy-fluorouridine(DFUR)/Doxifluridine
(+)-5-FLUORO-5'-DEOXYURIDINE 97%
5-FLURO-5’-DEOXYURIDINE
5Deoxy-5-fluorouridine, 5DFUR, 5dFUrd, Ro-21-9738
Doxifluidine
DOXIFLURIDINE(SUBJECTTOPATENTFREE)
(+)-5-Fluoro-5'-deoxyuridine98%
5-Fluorodesoxyuridine
Uridine, 5'-deoxy-5-fluoro- (8CI, 9CI)
5-FLUORO-5''-DEOXYURIDINE / DOXIFLURIDINE / 5''-DEOXY-FLUOROURIDINE
(+)-Doxifluridine, (+)-1-(beta-D-5'-Deoxyribofuranosyl)-5-fluorouracil
5-F-5‘-dU
5'-DFUR-13C5 (5'-Deoxy-5-fluorouridine, Doxifluridine-13C5)
AMC 0101
5-cl-5'-dU
Doxifluridine, >=98.5%
Capecitabine USP RC B
Doxifluridine Doxifluridine
5’-deoxy-5-fluoro-uridin
Doxifluridine/5-Fluoro-5′-deoxyuridine
Capecitabine Impurity 16（Capecitabine EP Impurity B）
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyl-2-oxolanyl]-5-fluoropyrimidine-2,4-dione
Capecitabine Impurity B
5'-Deoxy-5-fluorouridine>
Capecitabine EP Impurity B (5'-DFUR, Doxifluridine)
5’-deoxy-5-fluorouridine, Doxifluridine 5'-DFUR
Doxifluridine USP/EP/BP
Capecitabine EP Impurity B/ Capecitabine Related Compund B (Doxifluridine/ Deoxy-5-fluorouridine)