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ZL0454

ZL0454 structure

CAS No.: 2229042-77-5

Chemical Name:: ZL0454

Synonyms: ZL0454;ZL0454,ZL-0454;Benzenesulfonamide, 4-[(1E)-2-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-cyclopentyl-

CBNumber:: CB44668703

Molecular Formula:: C18H22N4O3S

Molecular Weight:: 374.46

MDL Number:: MFCD31813659

MOL File:: 2229042-77-5.mol

Last updated:2024-07-02 08:55:09

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ZL0454 Properties

Boiling point	630.6±65.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 50 mg/mL (133.53 mM; Need ultrasonic)
pka	9.30±0.36(Predicted)
form	Solid
color	Brown to reddish brown

ZL0454 Chemical Properties,Uses,Production

Biological Activity

ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.

References

[1]. Liu Z, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.

ZL0454 Preparation Products And Raw materials

Raw materials

Preparation Products

ZL0454 Suppliers

Global( 8)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58
cjbscvictory	13348960310 13348960310	3003867561@qq.com	China	10011	58
InvivoChem	13549236410	sales@invivochem.cn	China	6749	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9282	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
InvivoChem	58
Fan De(Beijing) Biotechnology Co., Ltd.	58
cjbscvictory	58
InvivoChem	58
TargetMol Chemicals Inc.	58
RD International Technology Co., Limited	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

2229042-77-5(ZL0454)Related Search:

ZLN005 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid ZL0420

ZL0454 ZL0454,ZL-0454 Benzenesulfonamide, 4-[(1E)-2-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-cyclopentyl- 2229042-77-5