AROTINOLOL
- CAS No.
- 68377-92-4
- Chemical Name:
- AROTINOLOL
- Synonyms
- Arot-API;Arotinolo;NSC 317940;Arottnolol;AROTINOLOL;Arotinolol (Almarl);Arotinolol free base;AROTINOLOL USP/EP/BP;5-(2-((3-(tert-Butylamino);Arotinolol Solution, 100ppm
- CBNumber:
- CB4486237
- Molecular Formula:
- C15H21N3O2S3
- Molecular Weight:
- 371.54
- MDL Number:
- MFCD00865895
- MOL File:
- 68377-92-4.mol
- MSDS File:
- SDS
| Melting point | 148-149° |
|---|---|
| Boiling point | 599.8±60.0 °C(Predicted) |
| Density | 1.35 |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 13.71±0.20(Predicted) |
| form | Solid |
| color | Off-White to Pale Yellow |
| FDA UNII | 394E3P3B99 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
AROTINOLOL price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A771500 | Arotinolol | 68377-92-4 | 100mg | $185 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA41108 | Arotinolol | 68377-92-4 | 25mg | $200 | 2021-12-16 | Buy |
| ChemScene | CS-0102757 | Arotinolol 98.18% | 68377-92-4 | 5mg | $90 | 2021-12-16 | Buy |
| AK Scientific | K136 | Arotinolol | 68377-92-4 | 5mg | $95 | 2021-12-16 | Buy |
| ChemScene | CS-0102757 | Arotinolol 98.18% | 68377-92-4 | 10mg | $150 | 2021-12-16 | Buy |
AROTINOLOL Chemical Properties,Uses,Production
Originator
Arotinolol,ZYF Pharm
Uses
Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension.
Definition
ChEBI: Arotinolol is a member of thiophenes and an aromatic amide.
Manufacturing Process
To a solution of 2-mercapto-4-(5'-carbamoyl-2'-thiophenyl)thiazole, 3.2 g in
20 ml of 0.3 % aqueous sodium hydroxide solution, 1-chloro-3-tbutylaminopropanol,
12.64 g in 20 ml of methanol was added, while the
temperature was maintained at 20°C.
The reaction solution was stirred at room temperature for 4 h, and then
condensed to a half volume in vacuo. The residual solution, added with 100 ml
of water, was extracted with chloroform. The chloroform extract was washed
with water, dried over anhydrous magnesium sulfate and evaporated in vacuo
to give 4.8 g of 2-(3'-t-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'-
thiophenyl)thiazole, as crystals, melting point 234°-235.5°C (dec.,
recrystallized from methanol/water).
In practice it is usually used as hydrochloride.
Therapeutic Function
Beta-adrenergic blocker
AROTINOLOL Preparation Products And Raw materials
AROTINOLOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7724 | 58 |
| Shijiazhuang Gantuo Biotechnology Co., Ltd | +8613373514458 | gantuo02@cngantuo.com | China | 203 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3512 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from AROTINOLOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-22 | AROTINOLOL
68377-92-4
|
US $1.00 / g | 1g | 85.0-99.8% | 20ton | Career Henan Chemica Co | |
 |
2023-06-26 | Arotinolol
68377-92-4
|
US $200.00 / kg | 1kg | 99% | 1000kg/Month | Hebei Mingeng Biotechnology Co., Ltd | |
 |
2023-04-11 | Arotinolol
68377-92-4
|
US $100.00 / KG | 25KG | 99% | 1000 Kilogram/Kilograms per Week | Shijiazhuang Gantuo Biotechnology Co., Ltd |
-
- AROTINOLOL
68377-92-4
- US $1.00 / g
- 85.0-99.8%
- Career Henan Chemica Co
-
- Arotinolol
68377-92-4
- US $200.00 / kg
- 99%
- Hebei Mingeng Biotechnology Co., Ltd
-
- Arotinolol
68377-92-4
- US $100.00 / KG
- 99%
- Shijiazhuang Gantuo Biotechnology Co., Ltd