ChemicalBook >> CAS DataBase List >>FOSINOPRILAT
FOSINOPRILAT
- CAS No.
- 95399-71-6
- Chemical Name:
- FOSINOPRILAT
- Synonyms
- SQ-27519;Fospenopril;Fosfenopril;FOSINOPRILAT;Forsinoprilat;Fosinoprilat-D5;fosinoprilicacid;Fosinopril diacid;Fosinopril Impurity;SQ 27519 Disodium Salt
- CBNumber:
- CB4711162
- Molecular Formula:
- C23H34NO5P
- Molecular Weight:
- 435.49
- MDL Number:
- MFCD00865781
- MOL File:
- 95399-71-6.mol
Last updated:2025-04-17 18:22:24
| Melting point | >3000C |
|---|---|
| alpha | D -24° (c = 1 in methanol) |
| Boiling point | 728.9±60.0 °C(Predicted) |
| Density | 1.238±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Methanol (Slightly), Water (Slightly) |
| pka | 2.75±0.50(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| FDA UNII | S312EY6ZT8 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360 |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| WGK Germany | 3 |
| HS Code | 2933995300 |
FOSINOPRILAT price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1283415 | Fosinopril Related Compound A | 95399-71-6 | 25mg | $1380 | 2024-03-01 | Buy |
| TRC | F727810 | FosinoprilatDisodiumSalt | 95399-71-6 | 50mg | $1390 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000568 | FOSINOPRILAT DISODIUM SALT 95.00% | 95399-71-6 | 50MG | $1963.5 | 2021-12-16 | Buy |
| AK Scientific | 8130AH | Fosinoprilat | 95399-71-6 | 5mg | $181 | 2021-12-16 | Buy |
| AK Scientific | 8130AH | Fosinoprilat | 95399-71-6 | 10mg | $314 | 2021-12-16 | Buy |
FOSINOPRILAT Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
A metabolite of Fosinopril, a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor
Uses
Fosinoprilat (Fosinopril EP Impurity A) is a metabolite of Fosinopril (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor.
Definition
ChEBI: A phosphinic acid-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. An inhibitor of angiotensin converting enzyme (ACE), it is used as the phosphinate ester pro-drug fosinopril for treatment of ypertension and chronic heart failure.
in vivo
Fosfenopril (0.5 mg/kg bolus plus 0.1 mg/kg/min, IV, once) increases p-aminohippurate (PAH) clearance and glomerular filtration rate (GFR) in dogs[3].
| Animal Model: | Famale mongrel dogs (n=7)[3] |
| Dosage: | 0.5 mg/kg (1.1 mumol/kg) bolus plus 0.1 mg/kg/min (0.22 mumol/kg/min) |
| Administration: | IV, once |
| Result: | Increased p-aminohippurate (PAH) clearance and glomerular filtration rate (GFR) by 25 and 16%, respectively without changing arterial pressure (AP). |
IC 50
TLR4; NF-κB; IL-6; IL-1β
FOSINOPRILAT Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 70)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Moxin Chemicals | +8617320513646 | Anna@molcoo.com | China | 9684 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Guangzhou PI PI Biotech Inc | 020-81716320 +86-13602409664 | Sales@pipitech.com | China | 3633 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Supplier | Advantage |
|---|---|
| Moxin Chemicals | 58 |
| BOC Sciences | 58 |
| TargetMol Chemicals Inc. | 58 |
| Nextpeptide Inc | 58 |
| sgtlifesciences pvt ltd | 58 |
| Aladdin Scientific | 58 |
| Amadis Chemical Company Limited | 58 |
| Guangzhou PI PI Biotech Inc | 55 |
| J & K SCIENTIFIC LTD. | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 50 |
View Lastest Price from FOSINOPRILAT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | Fosinopril EP Impurity A
95399-71-6
|
US $0.00-0.00 / mg | 20mg | 98 | 1000000 | Moxin Chemicals |
-
- Fosinopril EP Impurity A
95399-71-6
- US $0.00-0.00 / mg
- 98
- Moxin Chemicals
95399-71-6(FOSINOPRILAT)Related Search:
Fosinopril sodium
Fluvastatin sodium salt
BIDNLKIUORFRQP-FKDWWROVSA-N
1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline
trans-4-Cyclohexyl-L-proline hydrochloride
sodium:(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-[4-(2,3,4,5,6-pentadeuteriophenyl)butyl]phosphoryl]acetyl]pyrrolidine-2-carboxylate
Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid
PILSICAINIDE
Losartan potassium
FLUTICASONE PROPIONATE, 17-BETA CARBOXYLIC ACID
1of4
FOSINOPRILAT
fosinoprilicacid
Forsinoprilat
4β-Cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline
Fosfenopril
Fospenopril
SQ-27519
Fosinopril Related Compound A (25 mg) ((4S)-4-cyclohexyl-[(4-phenylbutyl)phosphinyl]acetyl-L-proline)
(4S)-4-Cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline Disodium Salt
Fosfenopril Disodium Salt
Fosinoprilat Disodium Salt
Fosinoprilic Acid Disodium Salt
SQ 27519 Disodium Salt
L-Proline, 4-cyclohexyl-1-hydroxy(4-phenylbutyl)phosphinylacetyl-, (4S)-
Fosinoprilat-D5
(4S)-4-Cyclohexyl-1-{[hydroxy(4-phenylbutyl)phosphinyl]acetyl}-L-proline
Fosinopril EP Impurity A
Fosinoprilat (Fosinopril IMpurity B)
Fosinopril EP impurity A -N
(4S)-4-Cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline
Fosinoprilat Solution, 100ppm
Fosinoprilat (Fosinopril EP Impurity A)
Fosinopril Sodium Impurity 1（Fosinopril Sodium EP Impurity A)
L-Proline, 4-cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-, (4S)-
Fosinopril EP Impurity A/ Fosinopril Related Compound A (Fosinoprilat)
(4S)-4-Cyclohexyl-[(4-phenylbutyl)phosphinyl]acetyl-L-proline
Fosinopril diacid
Fosinopril USP Related Compound A
Fosinopril Sodium EP Impurity A
Fosinopril EP Impurity A (Fosinopril USP Related Compound A, Fosinoprilat)
Fosinopril Impurity
95399-71-6
C23H28NO5P
C23H34NO5P
C23H32NNa2O5P
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
Aromatics
Chiral Reagents
Phosphorylating and Phosphitylating Agents
Various Metabolites and Impurities
Isotopically Labeled Pharmaceutical Reference Standard