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3,5-Difluoropyridine

CAS No.
71902-33-5
Chemical Name:
3,5-Difluoropyridine
Synonyms
3,5-Difluropyridine;3,5-DIFLUOROPYRIDINE;Pyridine, 3,5-difluoro-;3,5-Difluoropyridine>3,5-Difluoropyridine98%;3,5-Difluoropyridine 98%;3,5-Difluoropyridine ISO 9001:2015 REACH
CBNumber:
CB4751533
Molecular Formula:
C5H3F2N
Molecular Weight:
115.08
MDL Number:
MFCD03412222
MOL File:
71902-33-5.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

3,5-Difluoropyridine Properties

Boiling point 92-93°C
Density 1.256 g/mL at 25 °C
refractive index 1.4437
Flash point 9°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form clear liquid
pka 0.39±0.20(Predicted)
color Colorless to Almost colorless
BRN 7914363
InChIKey WRXAZPPGFLETFR-UHFFFAOYSA-N
CAS DataBase Reference 71902-33-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07,GHS09
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H315-H319-H335-H400
Precautionary statements  P210-P273-P280-P301+P312-P303+P361+P353-P304+P340+P312
Hazard Codes  Xi,F,N,Xn
Risk Statements  36/37/38-50-20/21/22-11
Safety Statements  26-36/37/39-61-36/37
RIDADR  1993
WGK Germany  3
Hazard Note  Highly Flammable/Irritant
HazardClass  3
PackingGroup  II
HS Code  29333990
NFPA 704
3
2 0

3,5-Difluoropyridine price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 703923 3,5-Difluoropyridine 97% 71902-33-5 5g $167 2023-06-20 Buy
TCI Chemical D4038 3,5-Difluoropyridine >98.0%(GC) 71902-33-5 1g $21 2024-03-01 Buy
TCI Chemical D4038 3,5-Difluoropyridine >98.0%(GC) 71902-33-5 5g $81 2024-03-01 Buy
Alfa Aesar L19539 3,5-Difluoropyridine, 98% 71902-33-5 1g $52.65 2024-03-01 Buy
Alfa Aesar L19539 3,5-Difluoropyridine, 98% 71902-33-5 5g $162.65 2024-03-01 Buy
Product number Packaging Price Buy
703923 5g $167 Buy
D4038 1g $21 Buy
D4038 5g $81 Buy
L19539 1g $52.65 Buy
L19539 5g $162.65 Buy

3,5-Difluoropyridine Chemical Properties,Uses,Production

Synthesis

Hydrogenolysis of 2,4,6-tribromo-3,5-difluoropyridine occurred rapidly giving quantitative conversion to 3,5-difluoropyridine (5), with an isolated yield by distillation of 63%.

Chemical Properties

Liquid

Preparation

Synthesis of 3,5-Difluoropyridine: A solution of 2,4,6-tribromo-3,5-difluoropyridine (11) (34.0 g, 97 mmol) in DCM (200 cm3) was washed with activated carbon and filtered. A palladium catalyst (3.4 g of a 5% Pd/C commercially available product) and triethylamine (45 cm3, 31.5 g, 312 mmol) were added to the filtrate and the mixture hydrogenated in a Parr apparatus at 4 Bar for 21 h. The mixture was filtered, water (200 cm3) added and extracted into DCM. Distillation of the DCM solution on Fischer-Spaltrohr apparatus gave 3,5-difluoropyridine (7.0 g, 61 mmol, 63%), b.p. 92.5 ·c (Found: C, 52.2; H, 3.0; N, 12.2. C5H3F2N2 requires C, 52.2; H, 3.0; N, 12.2%);
IR spectrum no. 1; mass spectrum no. 1; nrnr spectrum no. 8.

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View Lastest Price from 3,5-Difluoropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Difluoropyridine pictures 2024-04-17 3,5-Difluoropyridine
71902-33-5
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
3,5-Difluoropyridine pictures 2019-07-06 3,5-Difluoropyridine
71902-33-5
US $3.00 / KG 1KG 90%-99.9% 500kg Career Henan Chemical Co
3,5-DIFLUOROPYRIDINE 3,5-Difluoropyridine 98% 3,5-Difluoropyridine98% 3,5-Difluropyridine 3,5-Difluoropyridine> Pyridine, 3,5-difluoro- 3,5-Difluoropyridine ISO 9001:2015 REACH 71902-33-5 C5H3NF2 Fluorine series Pyridines, Pyrimidines, Purines and Pteredines Halides Pyridines Pyridine Chemical Synthesis Halogenated Heterocycles Heterocyclic Building BlocksHeterocyclic Building Blocks New Products for Chemical Synthesis Fluorin-contained pyridine series