Flumethasone 21-pivalate
- CAS No.
- 2002-29-1
- Chemical Name:
- Flumethasone 21-pivalate
- Synonyms
- Losalen;Lorinden;locorten;locacorten;NSC 107680;21-pivalate;FLUMETHSONEPIVALATE;FLUMETHASONE PIVALATE;Flumethasome pivalate;flumetasone 21-pivalate
- CBNumber:
- CB4762018
- Molecular Formula:
- C27H36F2O6
- Molecular Weight:
- 494.57
- MDL Number:
- MFCD00079287
- MOL File:
- 2002-29-1.mol
Melting point | >263°C (dec.) |
---|---|
Boiling point | 600.3±55.0 °C(Predicted) |
Density | 1.27±0.1 g/cm3(Predicted) |
storage temp. | Refrigerator |
solubility | dioxane: soluble4.0ML, clear, colorless to very faintly yellow (50 mg + 4.0 mL dioxane) |
form | solid |
pka | 11.86±0.70(Predicted) |
color | White to Off-White |
optical activity | [α]25/D 71.0 to 82.0°, c = 1 in dioxane |
CAS DataBase Reference | 2002-29-1(CAS DataBase Reference) |
FDA UNII | 0DV09X6F21 |
EPA Substance Registry System | Flumethasone-21-pivalate (2002-29-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H351 |
Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
Hazard Codes | Xn |
Risk Statements | 40 |
Safety Statements | 22-36 |
WGK Germany | 3 |
RTECS | TU3832010 |
HS Code | 2937220000 |
Toxicity | mouse,LD50,oral,> 5gm/kg (5000mg/kg),Drugs in Japan Vol. 6, Pg. 705, 1982. |
Flumethasone 21-pivalate price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | F0891 | Flumethasone pivalate | 2002-29-1 | 100mg | $177 | 2023-06-20 | Buy |
Sigma-Aldrich | F0188500 | Flumethasone pivalate European Pharmacopoeia (EP) Reference Standard | 2002-29-1 | f0188500 | $153 | 2024-03-01 | Buy |
TRC | F455015 | Flumethasone21-Pivalate | 2002-29-1 | 10mg | $65 | 2021-12-16 | Buy |
TRC | F455015 | Flumethasone21-Pivalate | 2002-29-1 | 50mg | $110 | 2021-12-16 | Buy |
AK Scientific | Q560 | Flumethasone pivalate | 2002-29-1 | 100mg | $238 | 2021-12-16 | Buy |
Flumethasone 21-pivalate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
An anti-inflammatory anti-itching corticosteroid found in topical creams.
Uses
flumethasone pivalate is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a pivalate, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Definition
ChEBI: Flumethasone pivalate is a pivalate ester, a glucocorticoid, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug and an antipruritic drug. It is functionally related to a flumethasone.
brand name
Locorten (Novartis).
Flumethasone 21-pivalate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 +86-15850508050 | sean.lv@synzest.com | China | 323 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
Henan Alfa Chemical Co., Ltd | China | 11415 | 58 | ||
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18151 | 58 |
PT CHEM GROUP LIMITED | +86-85511178; +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49978 | 58 |
View Lastest Price from Flumethasone 21-pivalate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | Flumethasone pivalate
2002-29-1
|
US $55.00-139.00 / mg | 99.56% | 10g | TargetMol Chemicals Inc. | |||
2024-04-25 | Flumethasone Pivalate
2002-29-1
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd |
- Flumethasone pivalate
2002-29-1
- US $55.00-139.00 / mg
- 99.56%
- TargetMol Chemicals Inc.
- Flumethasone Pivalate
2002-29-1
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd