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CILAZAPRIL

CAS No.
92077-78-6
Chemical Name:
CILAZAPRIL
Synonyms
Justor;Dynorm;Vascase;Initiss;Inhibace;Cilazapril CRS;CILAZAPRIL EPC(;Cilazapril Hydrate;Vascace monohydrate;ro31-2848monohydrate
CBNumber:
CB4771690
Molecular Formula:
C22H31N3O5.H2O
Molecular Weight:
435.51
MDL Number:
MFCD01692810
MOL File:
92077-78-6.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

CILAZAPRIL Properties

Melting point 98° (dec)
alpha D20 -62.51° (c = 1% in ethanol)
storage temp. Store at -20°C
solubility Slightly soluble in water, freely soluble in methanol and in methylene chloride.
form Solid
pka pKa1 3.3; pKa2 6.4(at 25℃)
color White to off-white
FDA UNII 19KW7PI29F
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

CILAZAPRIL price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C2174000 Cilazapril European Pharmacopoeia (EP) Reference Standard 92077-78-6 c2174000 $153 2024-03-01 Buy
Biosynth Carbosynth FC34997 Cilazapril monohydrate 92077-78-6 25mg $185 2021-12-16 Buy
Biosynth Carbosynth FC34997 Cilazapril monohydrate 92077-78-6 10mg $95 2021-12-16 Buy
ChemScene CS-2448 Cilazaprilmonohydrate 99.44% 92077-78-6 10mg $108 2021-12-16 Buy
Biosynth Carbosynth FC34997 Cilazapril monohydrate 92077-78-6 5mg $60 2021-12-16 Buy
Product number Packaging Price Buy
C2174000 c2174000 $153 Buy
FC34997 25mg $185 Buy
FC34997 10mg $95 Buy
CS-2448 10mg $108 Buy
FC34997 5mg $60 Buy

CILAZAPRIL Chemical Properties,Uses,Production

Description

Cilazapril is a new ACE inhibitor useful in the management of mild to moderate hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is more potent and longer lasting.

Chemical Properties

White or almost white, crystalline powder.

Originator

Hoffmann-LaRoche (Switzerland)

Uses

Antihypertensive.

Definition

ChEBI: Cilazapril monohydrate is a hydrate that is the monohydrate of cilazapril. It is used for the treatment of hypertension and heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It contains a cilazapril.

brand name

Inhibace (Hoffmann-LaRoche).

CILAZAPRIL Preparation Products And Raw materials

Global( 75)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29730 60
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49732 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 7859 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15393 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38636 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19889 58

View Lastest Price from CILAZAPRIL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cilazapril Monohydrate pictures 2024-11-19 Cilazapril Monohydrate
92077-78-6
US $198.00 / mg 10g TargetMol Chemicals Inc.
Cilazapril pictures 2020-05-10 Cilazapril
92077-78-6
US $0.00-0.00 / Kg 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
Cilazapril (monohydrate) pictures 2020-01-13 Cilazapril (monohydrate)
92077-78-6
US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co
  • Cilazapril pictures
  • Cilazapril
    92077-78-6
  • US $0.00-0.00 / Kg
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd
Initiss Justor Vascase 9[[1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]OCTAHYDRO-10-OXO-6HPYRIDAZINO[1,2-A][1,2]DIAZEPINE-1-CARBOXYLIC ACID CILAZAPRIL EPC( CILAZAPRIL EPC(CRM STANDARD) CILAZAPRIL IMPURITY A1,1-DIMETHYLETHYL(1S,9S)-9-[[(S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]-10-OXO-OCTAHYDRO-6H-PYRIDAZINO[1,2A][1,2]DIAZEPINE-1-CABOXYLATE EPC [1S-[1α,9α(R^<*>^)]]-9-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-α][1,2]diazepine-1-carboxylic acid monohydrate 9-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-10-oxo-1,2,3,4,6,7,8,9-oc tahydropyridazino[1,2-a]diazepine-1-carboxylic acid Inhibace (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]aMino}-1-hydroxy-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid Cilazapril Monohydrate (Inhibace) 6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylicacid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]octahydro-10-oxo-,hydrate (1:1), (1S,9S)- (1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, hydrate (1:1) (1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate (1S,9S)-9-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate (1:1) 6h-pyridazino(1,2-a)(1,2)diazepine-1-carboxylicacid,octahydro-9-((1-(ethoxyca cilazaprilmonohydrate hydrate,(1s-(1-alpha,9-alpha(r*)))-rbonyl)-3-phenylpropyl)amino)-10-oxo ro31-2848monohydrate (1s,9s)-9-[(s)-1-ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid Cilazapril Hydrate Inhibace monohydrate INHIBACE MONOHYDRATE;RO 31-2848 MONOHYDRATE;VASCACE MONOHYDRATE Vascace monohydrate Cilazapril CRS (1S,9S)-9-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-10-oxooctahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid Cilazapril Monohydrate (Ro 31-2848) (1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-10-oxooctahydro-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylicacidmonohydrate Dynorm 92077-78-6 C22H31N3O5H2O Inhibitors