ChemicalBook >> CAS DataBase List >>Methoxy-Tr-NH-PEG7
Methoxy-Tr-NH-PEG7
- CAS No.
- 2353409-88-6
- Chemical Name:
- Methoxy-Tr-NH-PEG7
- Synonyms
- Methoxy-Tr-NH-PEG7;(4-methoxyphenyl)diphenylmethylamino-PEG7;3,6,9,12,15,18-Hexaoxa-21-azadocosan-1-ol, 22-(4-methoxyphenyl)-22,22-diphenyl-
- CBNumber:
- CB48054753
- Molecular Formula:
- C34H47NO8
- Molecular Weight:
- 597.74
- MDL Number:
- MFCD31811509
- MOL File:
- 2353409-88-6.mol
Last updated:2023-02-23 14:24:01
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Methoxy-Tr-NH-PEG7 Chemical Properties,Uses,Production
Biological Activity
Methoxy-Tr-NH-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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Methoxy-Tr-NH-PEG7
(4-methoxyphenyl)diphenylmethylamino-PEG7
3,6,9,12,15,18-Hexaoxa-21-azadocosan-1-ol, 22-(4-methoxyphenyl)-22,22-diphenyl-
2353409-88-6