pholedrine sulphate
- CAS No.
- 6114-26-7
- Chemical Name:
- pholedrine sulphate
- Synonyms
- pholedrine sulphate;4-(2-(METHYLAMINO)PROPYL)PHENOL HEMISULFATE
- CBNumber:
- CB4879569
- Molecular Formula:
- C20H32N2O6S
- Molecular Weight:
- 428.54288
- MDL Number:
- MOL File:
- 6114-26-7.mol
Last updated:2023-05-04 15:16:17
| FDA UNII | WB6LNL73BR |
|---|
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H335-H315-H318-H300 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P310-P321-P330-P405-P501 |
| Toxicity | LD s.c. in rats: 500 mg/kg (Lindner) |
pholedrine sulphate Chemical Properties,Uses,Production
Originator
Pholedrine Sulfate, ZYF Pharm Chemical
Manufacturing Process
100 g β-(methoxyphenyl)isopropylamine prepared, for example by reduction of p-methoxybenzylmethylketone with hydrogen and nickel catalyst in presence of ammonia or by Mannix's method, 250 ml ethanol and calculated quantity of solution of formaldehyde and 70 g activated aluminum shaving were heated for 6 hours by stirring. The mixture was filtered, the solvent was removed in vacuum and the residue was dissolved in ethanol contained hydrochloric acid. The prepared hydrochloride of β-(pmethoxyphenyl)isopropylmethylamine had MP: 174°C.
In practice it is usually used as sulfate.
Therapeutic Function
Sympathomimetic, Mydriatic, Analeptic, Vasopressor
pholedrine sulphate Preparation Products And Raw materials
pholedrine sulphate
4-(2-(METHYLAMINO)PROPYL)PHENOL HEMISULFATE
6114-26-7